Common Pain Mechanisms in Migraine and Associated Neck and Lower Back Pain

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational cross-sectional study investigates whether central sensitization and related pain processing changes are common across migraine, neck pain, and low back pain. Participants aged 18-65 who have migraines and concurrent neck or lower back pain, and Turkish readers, will complete questionnaires to characterize pain sensitivity and symptoms. The study will compare migraine patients to control participants without migraine to identify potential shared mechanisms. No interventions are described; the focus is on measurement and correlation of symptoms and central pain processing indicators. The lead sponsor is Bozok University with a collaborating site at Gazi University in Gaziantep.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Being between 18 and 65 years of age,
* Being able to read and understand Turkish,
* Agreeing to participate voluntarily,
* Having an episodic or chronic migraine diagnosis according to the International Classification of Headache Disorders Edition 3 criteria;
* Having neck pain and/or lower back pain without any underlying diagnosis accompanying the migraine diagnosis.

Exclusion Criteria:

* A history of neurological disorder (e.g., Multiple Sclerosis),
* Inflammatory rheumatic disorders (e.g., Rheumatoid Arthritis), generalized chronic pain syndromes (e.g., Fibromyalgia),
* Any other headache disease, any other systemic disease,
* Acute fracture and infection,
* Spinal surgery or spinal disease diagnosis within the last 6 months,
* Serious musculoskeletal trauma within the last 6 months,
* Pregnancy,
* A cognitive or psychiatric condition that would prevent completion of the questionnaires,
* In the control group without a migraine diagnosis,
* A history of recurrent headaches within the last year.

Where it's running

• Gazi University
  Gaziantep, Merkez, Turkey (Türkiye) Recruiting

Study contacts

• Principal investigator: Dilara Onan, PhD — Yozgat Bozok University
• Study coordinator: Dilara ONAN, PhD
• Email: dilaraonan@gmail.com
• Phone: +905358642234

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.