Combining two methods for pain relief after knee surgery
Combined Intrathecal Dexmedetomidine and Adductor Canal Block for Analgesia After Total Knee Arthroplasty: A Randomized Controlled Trial
NA · Kafrelsheikh University · NCT06837844
This study is testing if using a combination of a nerve block and a medication can help people feel less pain after knee surgery.
Quick facts
| Phase | NA |
|---|---|
| Study type | Interventional |
| Enrollment | 75 (estimated) |
| Ages | 18 Years to 75 Years |
| Sex | All |
| Sponsor | Kafrelsheikh University (other) |
| Locations | 1 site (Kafr ash Shaykh, Kafrelsheikh) |
| Trial ID | NCT06837844 on ClinicalTrials.gov |
What this trial studies
This study evaluates the effectiveness of using both intrathecal dexmedetomidine and an adductor canal block for managing pain after total knee arthroplasty. The adductor canal block targets specific nerves to provide localized pain relief, while dexmedetomidine offers additional analgesic and sedative effects. The goal is to enhance postoperative pain management, promote early mobilization, and reduce complications associated with knee surgery.
Who should consider this trial
Good fit: Ideal candidates are adults aged 18 to 75 scheduled for total knee arthroplasty under spinal anesthesia with ASA physical status I-II.
Not a fit: Patients with neurological disabilities, allergies to local anesthetics or dexmedetomidine, or those with obesity (BMI > 30 kg/m2) may not benefit from this study.
Why it matters
Potential benefit: If successful, this approach could significantly improve pain management for patients undergoing total knee arthroplasty.
How similar studies have performed: While this approach combines established techniques, the specific combination of intrathecal dexmedetomidine and adductor canal block for this purpose is relatively novel.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Age from 18 to 75 years. * Both sexes. * American Society of Anesthesiology (ASA) physical status I-II. * Scheduled for total knee arthroplasty under spinal anesthesia. Exclusion Criteria: * Patients with neurological or intellectual disability. * History of allergy to local anesthetics or dexmedetomidine . * Infection at the injection site. * Prolonged use of analgesic or sedative medications. * Coagulation abnormalities. * Pregnancy. * Obesity \[body mass index (BMI) \> 30 kg/m2\].
Where this trial is running
Kafr ash Shaykh, Kafrelsheikh
- Kafrelsheikh University — Kafr ash Shaykh, Kafrelsheikh, Egypt (RECRUITING)
Study contacts
- Study coordinator: Sherif K Arafa, MD
- Email: Sherifhafez1980@gmail.com
- Phone: 00201005714014
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Intrathecal Dexmedetomidine, Adductor Canal Block, Analgesia, Total Knee Arthroplasty