Combining personal HPV story videos with informational vaccine animations to boost teen vaccination

"Facts Tell… and With Stories Sell?" Combining Viewer-tailored Personal HPV Narrative Video With HPV Vaccine Information Video to Improve HPV Vaccine Uptake

Not applicable Interventional Johns Hopkins Bloomberg School of Public Health · NCT06587243

We will test whether personal HPV story videos, informational HPV vaccine videos, or both together best help parents of 11–17-year-olds who haven't received the HPV vaccine decide to vaccinate.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment1100 (estimated)
SexAll
SponsorJohns Hopkins Bloomberg School of Public Health Academic / other
Locations1 site (New York, New York)
Trial IDNCT06587243 on ClinicalTrials.gov

What this trial studies

Parents of unvaccinated 11–17-year-olds are randomized to view either an informational animation, a personal narrative video, or both, and complete surveys before and after viewing. The study measures changes in vaccine intentions and short-term self-reported uptake after exposure to the videos. Videos are delivered and viewed on participants' own devices, and completion of the survey and video viewing are required for inclusion. The trial is run by Johns Hopkins Bloomberg School of Public Health with data-collection support from Ipsos and collaboration from Merck Sharp & Dohme.

Who should consider this trial

Good fit: Ideal candidates are parents or legal guardians of 11–17-year-old adolescents who have not yet received any HPV vaccine doses and can view videos on their device.

Not a fit: Parents whose adolescents are already vaccinated or who cannot or will not view videos on their device are unlikely to benefit from participation.

Why it matters

Potential benefit: If successful, the approach could increase HPV vaccine uptake by identifying which video format most motivates parents to vaccinate their teens.

How similar studies have performed: Prior research shows mixed but promising results for narrative and informational messaging separately, while combining tailored personal narratives with information is less well tested.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Parents of 11-17 year olds not yet vaccinated against HPV

Exclusion Criteria:

* Parents whose adolescent children are already vaccinated against HPV
* Participants who do not complete the survey
* Participants who are unable or refuse to view and listen to videos on the participant's device

Where this trial is running

New York, New York

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions VaccinationHPVVaccineNarrativeCommunicationVideos
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.