Combining Dlbs 3233 with clomiphene citrate for PCOS
Official title: The Effect of Combination Therapy Dlbs 3233 and Clomifen Citrate vs Clomifen Citrate on Homa ir, Maturation Follicle, and Menstrual Cycle in PCOS Cases at Muhammadiyah Asri Medical Center Hospital
Run by Inlacinpenelitian · NCT07403201 · Data updated 2026-11-12
This will test whether adding Dlbs 3233 to clomiphene citrate helps women with PCOS improve insulin resistance (HOMA-IR), follicle maturation, and menstrual cycle regularity.
Quick facts
| Phase | Early Phase 1 |
|---|---|
| Study type | Interventional |
| Ages | Any age to 45 Years |
| Sex | Women only |
| Enrollment | 90 (estimated) |
| Sponsor | Inlacinpenelitian Academic / other |
| Locations | 1 site (Yogyakarta, DIY) |
| Status | Recruiting |
| Started | December 15, 2021 |
| Main results expected | January 31, 2026 |
| Study ends | January 31, 2026 |
| Registry record updated | February 11, 2026 |
| Trial ID | NCT07403201 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Women of reproductive age diagnosed with PCOS who are willing to take clomiphene citrate and Dlbs 3233 and can provide informed consent are the intended participants.
✕Probably not a fit
Women who cannot take clomiphene, have other primary causes of infertility, or significant medical comorbidities may not receive benefit from this approach.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This interventional early-phase study gives women with PCOS either a combination of Dlbs 3233 plus clomiphene citrate or clomiphene citrate alone and monitors outcomes. Key outcomes include changes in HOMA-IR (insulin resistance), maturation of ovarian follicles, and menstrual cycle patterns. The trial is conducted at RS AMC Yogyakarta and focuses on initial safety and early signals of benefit. Results will inform whether larger trials are warranted.
Why it matters
Potential benefit: If successful, the combination could improve metabolic control, promote ovulation, and help regularize menstrual cycles for women with PCOS.
How similar studies have gone: Clomiphene citrate is an established ovulation agent, but combining it with Dlbs 3233 appears novel and there is limited prior published data on this exact combination.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * married agree to join this research Exclusion Criteria: * dis agree to join research
Where it's running
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RS AMC Yogyakarta
Yogyakarta, Diy, Indonesia Recruiting
Study contacts
- Study coordinator: prastika candra, s1
- Email: prastikacandra13@gmail.com
- Phone: 62882003145445
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.