Clinical trial Recruiting at 1 site Interventional Ages 18 and up

Combining acupuncture, acupressure, and nicotine therapy to help quit smoking

Official title: Combination of Acupuncture, Auricular Acupressure and Nicotine Replacement Therapy for Smoking Cessation: A Randomized Controlled Trial

Run by The University of Hong Kong · NCT06931054 · Data updated 2026-11-12

This study is testing if a mix of acupuncture, acupressure, and nicotine therapy can help people quit smoking better than just using nicotine therapy alone.

More Smoking trials

Quick facts

Study typeInterventional
Ages18 Years and up
SexAll
Enrollment270 (estimated)
SponsorThe University of Hong Kong
Academic / other
Locations1 site (Hong Kong)
StatusRecruiting
StartedMay 5, 2025
Main results expectedOctober 30, 2026
Study endsOctober 30, 2026
Registry record updatedMay 11, 2025
Trial IDNCT06931054 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates are adults aged 18 or older who smoke at least 10 cigarettes per day and can read and write in Chinese.

Probably not a fit

Patients with a history of severe adverse reactions to acupuncture or those currently using other smoking cessation services may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study evaluates the effectiveness of a combined treatment approach for smoking cessation that includes acupuncture, auricular acupressure, and nicotine replacement therapy (NRT). Participants will be randomly assigned to one of three groups: one receiving the combined treatment, one receiving a sham treatment, and one receiving NRT with standard consultation. The study aims to determine if the combination therapy improves smoking cessation rates, reduces withdrawal symptoms, and increases side effects compared to NRT alone. A total of 270 participants will be enrolled, with each group consisting of 90 individuals.

Why it matters

Potential benefit: If successful, this approach could significantly improve smoking cessation rates for individuals trying to quit smoking.

How similar studies have gone: Previous studies have shown promising results for acupuncture and acupressure in smoking cessation, but this specific combination approach is relatively novel.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

1. Individuals aged 18 or older.
2. Individuals who consume at least 10 traditional cigarettes per day.
3. Individuals with access to a smartphone for communication and internet use.
4. Individuals who are able to read and write Chinese.

Exclusion Criteria:

1. Previous use of acupuncture for smoking cessation or any other condition.
2. Skin problems related to diabetes.
3. Hyperthyroidism.
4. Hospitalized at Intensive Care Unit in the past 4 weeks.
5. Severe cardiovascular diseases.
6. Pregnancy.
7. Breastfeeding.
8. History of severe adverse reactions to acupuncture.
9. Current use of blood-thinning medication or having a bleeding disorder.
10. Current use of other smoking cessation services.

Where it's running

  • School of Nursing, The University of Hong Kong
    Hong Kong, Hong Kong
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.