Combining Acceptance and Commitment Therapy with Vestibular Rehabilitation for mTBI

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This clinical trial aims to compare the effectiveness of Acceptance and Commitment Therapy Integrated Vestibular Rehabilitation (ACTIVE) against standard vestibular rehabilitation (VESTIB CONTROL) in individuals with mild traumatic brain injury (mTBI) and related vestibular symptoms. Conducted at two sites, the University of Pittsburgh Medical Center and the Intrepid Spirit Center, the trial will enroll 250 participants who will receive treatment over four weeks. Assessments will be conducted at baseline, and at 4 weeks, 3 months, and 6 months post-treatment to evaluate outcomes related to vestibular symptoms and psychological health. The study seeks to address the challenges faced by military service members experiencing prolonged symptoms following mTBI.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* 18-49 years of age
* Normal/corrected vision
* Diagnosed with mTBI per military clinical practice guidelines (CPGs) that occurred over 8 days prior to consent as determined by a multi-domain assessment performed by a licensed healthcare professional.
* mTBI-related symptoms and/or impairments in at least one or more areas, including vestibular (dizziness, imbalance), psychological health (anxiety, depression, stress), cognitive (memory problems), headache/migraine, ocular, or sleep. as determined by self-report.

Exclusion Criteria:

* History of vestibular disorder (e.g., benign paroxysmal positional vertigo, unilateral or bilateral vestibular hypofunction) as determined by patient self-report.
* History of neurological disorder (e.g., epilepsy, multiple sclerosis) as determined by self-report.
* Cervical spine injury or dysfunction (i.e., limited range of motion; ROM) as determined by self-report.
* Previous moderate to severe TBI as determined by self-report.
* \< 8 days following current mTBI as determined by self-report.
* Currently pregnant as determined by self-report.

Where it's running

• University of Pittsburgh Concussion Research Laboratory
  Pittsburgh, Pennsylvania, United States Recruiting
• Intrepid Spirit Center, Carl R. Darnall Army Medical Center
  Fort Hood, Texas, United States Not yet recruiting

Study contacts

• Principal investigator: Anthony Kontos, PhD — University of Pittsburgh
• Study coordinator: Anthony Kontos, PhD
• Email: akontos@pitt.edu
• Phone: 814-615-2163

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• See if Man Therapy helps reduce problematic anger in male service members with or without a mild TBI

  This trial tests whether the Man Therapy online program can lower problematic anger in male military members who screen positive for anger, compared to a waitlist.

  Recruiting University of Colorado, Denver · Colorado Springs, Colorado · NCT07604701

• Motor Activation Therapy after concussion: a targeted rehabilitation approach

  This study tests a motor-activation focused physical therapy for people with persistent balance problems after a concussion to see if it improves their responses to imbalance.

  Recruiting at 2 sites Oregon Health and Science University · Portland, Oregon and 1 other locations · NCT07549529

• Biomarker-guided care for mild traumatic brain injury using GFAP and UCH-L1

  This project will try a blood test that measures GFAP and UCH-L1 to see if adults with recent mild traumatic brain injury can safely avoid a head CT.

  Recruiting Hospital Universitario 12 de Octubre · Madrid, Madrid · NCT07311486

• Tinted daily contact lenses for light sensitivity after a concussion

  This project will try daily disposable tinted contact lenses to reduce light sensitivity in adults who have had a mild concussion.

  Recruiting University of Alabama at Birmingham · Birmingham, Alabama · NCT07223086

• Cooling therapy for mild traumatic brain injury in adolescents

  This study is testing if a cooling device can help young athletes aged 12-21 recover better from mild brain injuries they got while playing sports.

  Recruiting TecTraum Inc. · Ann Arbor, Michigan and 2 other locations · NCT06929923

• Symptom-Targeted Rehabilitation for Concussion (STAR-C)

  This project will test whether in-person and telehealth STAR‑C help adults with past concussions reduce everyday cognitive complaints.

  Recruiting at 2 sites Henry M. Jackson Foundation for the Advancement of Military Medicine · Wahiawa, Hawaii and 1 other locations · NCT06855186

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.