Combined effects of low‑intensity resistance with blood flow restriction for upper limb strength after stroke

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

In this single-blinded randomized trial, 64 stroke patients aged 50–70 will be assigned to either low‑intensity resistance training with blood flow restriction (BFR) or conventional physical therapy. The BFR group uses 40% of 1‑RM with 2 kg weights and cuffs at 150–160 mmHg for 40 minutes, four days a week, for six weeks, while the control group performs standard sensorimotor and strengthening activities. Outcomes include upper-extremity function (Fugl-Meyer), forward reach (Functional Reach Test), and strength (ARAT), assessed at baseline and after the intervention. Data will be analyzed with appropriate parametric or nonparametric tests to compare intra- and intergroup changes.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* • 50 to 70 year of age (5)

  * Both males and females (5)
  * Generalized stroke population (both ischemic and hemorrhagic stroke) (9).
  * Post stroke patient after 1 month (5)
  * Barthel index scores ≥ 20 (10)
  * Spasticity level according to Modified Ashworth scale should be 1/+1 grade in the affected upper limb(7)
  * Muscle strength at grade 3 according to MMT of affected upper limb (7)

Exclusion Criteria:

* • People with a history of mental/cognitive illness (9)

  * History of transient ischemic attack (TIA) or recurrent stroke (8)
  * Diabetes with peripheral neuropathy (5)
  * Having resting blood pressure above 160/100 mmHg even after taking medications
  * Cardiovascular comorbidity (heart failure, unstable angina, aortic stenosis)

Where it's running

• Amin Welfare & Teaching Hospital
  Sialkot, Punjab Province, Pakistan Recruiting

Study contacts

• Principal investigator: Aiza Yousaf, MS-OMPT — Riphah International University
• Study coordinator: Imran Amjad, PhD
• Email: imran.amjad@riphah.edu.pk
• Phone: 03324390125

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Other studies for the same condition or treatment. Recruiting studies are listed first.

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.