Collection of blood and tissue samples for cardiac arrhythmias
Official title: Cleveland Clinic Arrhythmia Biospecimen Repository (Cleveland Clinic Arrhythmia BioBank)
Run by The Cleveland Clinic · NCT00921986 · Data updated 2026-11-12
This study is collecting blood and tissue samples from people with heart rhythm problems and healthy individuals to see if there are any genetic clues that could help us understand these conditions better.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 2000 (estimated) |
| Sponsor | The Cleveland Clinic Academic / other |
| Locations | 1 site (Cleveland, Ohio) |
| Status | Recruiting |
| Started | March 2009 |
| Main results expected | December 2035 |
| Study ends | December 2035 |
| Registry record updated | September 14, 2026 |
| Trial ID | NCT00921986 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates include individuals aged 18 and older with a history of cardiac arrhythmias or those who are family members of affected individuals.
✕Probably not a fit
Patients who have previously participated in the Arrhythmia BioBank will not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This research involves creating a biorepository of blood and tissue samples from patients with cardiac arrhythmia syndromes. The goal is to identify genetic factors and biological pathways associated with these conditions. The study will gather detailed phenotypic data alongside the samples from patients undergoing evaluations or treatments for arrhythmias, as well as control subjects without arrhythmias. The biorepository will consist of samples collected from both patients and collaborating institutions.
Why it matters
Potential benefit: If successful, this research could lead to a better understanding of the genetic causes of cardiac arrhythmias, potentially improving diagnosis and treatment options for patients.
How similar studies have gone: Other studies utilizing biorepositories for genetic research in cardiac conditions have shown promise, indicating that this approach is both relevant and potentially impactful.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Male or female at least 18 years old * Subjects with a history of or current cardiac arrhythmia, family members of subjects with cardiac arrhythmias, or no cardiac arrhythmia if a Control Subject. Exclusion Criteria: * Subjects previously enrolled in the Arrhythmia BioBank
Where it's running
-
Cleveland Clinic Foundation
Cleveland, Ohio, United States Recruiting
Study contacts
- Principal investigator: Mina K. Chung, MD — The Cleveland Clinic
- Study coordinator: Mina K. Chung, MD
- Email: chungm@ccf.org
- Phone: 216.444.2290
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
-
Can fluoroscopy plus TTE guidance improve leadless pacemaker placement accuracy
This study tests whether using transthoracic echocardiography (TTE) during leadless pacemaker placement improves accuracy and safety compared with standard fluoroscopy.
-
Dual Energy ThermoCool SmartTouch SF Catheter with TRUPULSE Generator for Ventricular Arrhythmias
This study tests a special catheter and generator setup to treat ventricular arrhythmias and checks that the procedure can be done safely following a specific workflow.
-
Volta AI software in real-world AF ablation
A real-world observational study will test the latest Volta AF-Xplorer II AI software during atrial fibrillation ablation to see how safe and effective it is over 24 months.
-
Pacing decisions guided by risk for pacing-induced heart muscle weakness
This study tests a risk score to predict pacing-induced cardiomyopathy in adults getting heart rhythm devices, to tailor pacing choices.
-
Heart assessment to check repeat-stroke risk in people with atrial fibrillation
This project will test whether detailed heart examinations can find which people with atrial fibrillation who just had an ischemic stroke are at high risk of having another stroke.
-
Sensor-guided exercise program for people with atrial fibrillation
This program will test whether a Fitbit-based, personalized exercise plan can reduce symptoms and episode burden in people with paroxysmal atrial fibrillation.
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.