Clinical trial Recruiting at 1 site Observational Ages 6 to 99

Collection of biological samples from patients with rare neurological diseases

Official title: Prospective Collection of Biological Samples From Patients With Rare Neurological Diseases

Run by University Hospital, Toulouse · NCT04698421 · Data updated 2026-11-12

This study is trying to collect biological samples from people with rare neurological diseases to see if they can find new markers that help diagnose and treat these conditions.

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Quick facts

Study typeObservational
Ages6 Years to 99 Years
SexAll
Enrollment1000 (estimated)
SponsorUniversity Hospital, Toulouse
Academic / other
Drugs / interventionsimmunotherapy
Locations1 site (Toulouse)
StatusRecruiting
StartedOctober 12, 2020
Main results expectedJanuary 1, 2030
Study endsSeptember 3, 2030
Registry record updatedMarch 19, 2026
Trial IDNCT04698421 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates include patients of all ages with neurological disorders that have known or probable autoimmune involvement.

Probably not a fit

Patients with neurological damage that is not autoimmune in nature or those with known anemia may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This project aims to enhance the collection of biological samples from patients suffering from rare neurological disorders with known or suspected autoimmune origins. By gathering these samples, the study seeks to identify new biomarkers that can aid in the diagnosis and treatment of these conditions. The focus is on disorders such as autoimmune encephalitis and paraneoplastic neurological syndromes, where the immune system plays a critical role. The collected samples will be made available to the medical and scientific communities to foster the development of new therapeutic strategies.

Why it matters

Potential benefit: If successful, this study could lead to improved diagnostic and prognostic tools for patients with rare neurological diseases.

How similar studies have gone: While the approach of collecting biological samples for autoimmune neurological disorders is established, the specific focus on rare conditions may present novel insights.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* all patients with neurological disorders, with known or probable autoimmune involvement. This includes adults and children and peripheral and/or central nervous system symptoms.
* Social coverage up to date.

Exclusion Criteria:

* Patients with neurological damage from which the autoimmune character can be excluded.
* Known anemia and hemoglobin \<10 g / dl
* Patients under protective supervision (guardianship, curators)
* Pregnant or breastfeeding woman

Where it's running

  • Purpan University Hospital
    Toulouse, France
    Recruiting

Study contacts

  • Principal investigator: Chloé Bost, PharmD, PhD — University Hospital, Toulouse
  • Study coordinator: Chloé Bost, PharmD, PhD
  • Email: bost.c@chu-toulouse.fr
  • Phone: 5 61 77 61 44

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.