Collection and analysis of biological samples from patients with multiple myeloma and related conditions

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to establish a common international infrastructure for the prospective collection, storage, and analysis of biological samples from patients diagnosed with multiple myeloma, smoldering multiple myeloma, plasma cell leukemia, and related conditions. It will gather standard clinical variables at baseline and during treatment to facilitate future research. The study involves multiple centers across Europe and focuses on creating a comprehensive biobank for better understanding and treatment of these conditions.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Subjects with MGUS, smouldering Multiple Myeloma (SMM) , MM (Multiple Myeloma) (+/- EMD), plasma cell leukemia (PCL) (+/- EMD)
* Subjects are ≥ 18 years old.
* Subjects have provided written informed consent in accordance with federal, local, and institutional guidelines prior to initiation of any project-specific activities or procedures.

  1. Subjects do not have kind of condition that, in the opinion of the Investigators, may compromise the ability of the subjects to give written informed consent and
  2. subjects are, in the investigator's opinion, willing and able to comply with the protocol requirements.

Exclusion Criteria:

* Previous treatment with anti-myeloma therapy (excluding one course of therapy in patients in which urgent therapy is deemed necessary according to physician's discretion, e.g. myeloma-related complications resistant to supportive care).
* Subjects have had prior unforeseen (serious) adverse reactions to blood donation including, but not limited to fainting, angina, severe bruising, allergic reactions, or any other adverse events.
* Any psychological, familial, sociological and geographical condition potentially hampering compliance with the protocol and follow-up schedule.

Where it's running

• Alfred Hospital
  Melbourne, Australia Recruiting
• KUK Linz
  Linz, Austria Recruiting
• Medical University Vienna
  Vienna, Austria Recruiting
• Department of Haematology UZ Leuven Gasthuisberg
  Leuven, Belgium Recruiting
• Nemocnice Havířov
  Havířov, Czechia Recruiting
• Nemocnice Nový Jičín
  Nový Jičín, Czechia Recruiting

Study contacts

• Study coordinator: Chiara Del Pietro
• Email: chiara.delpietro@emn.org
• Phone: +31 10702687065

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Other studies for the same condition or treatment. Recruiting studies are listed first.

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• Prolonged overnight fasting combined with a Mediterranean-style diet for people with multiple myeloma or precursor conditions

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• Combining JNJ-79635322 with Daratumumab or Pomalidomide for Multiple Myeloma Treatment

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.