Collecting real-world data on cancer patients treated with radiotherapy in Europe
Official title: E²-RADIatE: EORTC-ESTRO RADiotherapy InfrAstrucTure for Europe
Run by European Organisation for Research and Treatment of Cancer - EORTC · NCT03818503 · Data updated 2026-11-12
This study is collecting information from cancer patients receiving radiotherapy in Europe to see how well this treatment works alongside other therapies.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 12 Years and up |
| Sex | All |
| Enrollment | 2000 (estimated) |
| Sponsor | European Organisation for Research and Treatment of Cancer - EORTC Research network |
| Drugs / interventions | radiation |
| Locations | 77 sites (Graz and 76 other locations) |
| Status | Recruiting |
| Started | June 24, 2019 |
| Main results expected | April 30, 2026 |
| Study ends | April 30, 2026 |
| Registry record updated | March 21, 2025 |
| Trial ID | NCT03818503 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates include patients aged 12 years and older with pathologically confirmed cancer who are planned to receive radiotherapy.
✕Probably not a fit
Patients who do not have a confirmed cancer diagnosis or are not planned for radiotherapy will not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational study aims to gather real-world data from cancer patients who are undergoing radiotherapy. It focuses on understanding the role of radiation oncology within a multidisciplinary treatment approach. The study is non-interventional and will include multiple cohorts of patients, ensuring a comprehensive analysis of treatment outcomes. Participants will be monitored over time to provide valuable insights into the effectiveness of radiotherapy in cancer care.
Why it matters
Potential benefit: If successful, this study could enhance the understanding of radiotherapy's impact on cancer treatment and improve patient outcomes.
How similar studies have gone: Other studies collecting real-world data in oncology have shown success in improving treatment protocols and patient outcomes, indicating that this approach is promising.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Pathologically confirmed cancer. * Written informed consent for E²-RADIatE according to applicable legal and ethical requirements * Planned use of radiotherapy * Eligibility of the patient confirmed for at least one cohort confirmed * Patients of 12 years and older
Where it's running
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Medical University of Graz - Radio-oncology
Graz, Austria Recruiting -
Ordensklinikum Linz-Barmherzige Schwestern
Linz, Austria Recruiting -
Universitaetskliniken der Uni Wien - Universitaetsklinikum Wien - AKH unikliniken
Vienna, Austria Recruiting -
Cliniques Universitaires Saint-Luc
Brussels, Belgium Recruiting -
Institut Jules Bordet
Brussels, Belgium Recruiting -
Universitair Ziekenhuis Gent
Ghent, Belgium Recruiting
Show 44 more locations
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AZ Sint-Lucas & Volkskliniek
Ghent, Belgium Recruiting -
AZ Groeninge Kortrijk - Campus Kennedylaan
Kortrijk, Belgium Recruiting -
AZ Turnhout - Campus Sint Elisabeth
Turnhout, Belgium Recruiting -
GasthuisZusters Antwerpen - Sint-Augustinus
Wilrijk, Belgium Recruiting -
University Hospital Hradec Kralove
Hradec Králové, Czechia Recruiting -
Universitaetsklinikum Carl Gustav Carus
Dresden, Germany Recruiting -
Kliniken Maria Hilf GmbH
Mönchengladbach, Germany Recruiting -
Ludwig-Maximilians-Universitaet Muenchen - Campus Grosshadern
München, Germany Recruiting -
St Luke Hospital & SLRON - SLRON - St. Luke'S Hospital Rathgar
Dublin, Ireland Recruiting -
Beacon Hospital
Dublin, Ireland Recruiting -
University Hospital Galway
Galway, Ireland Recruiting -
Sheba Medical Center Tel Hashomer
Ramat Gan, Israel Recruiting -
Ente Ecclesiastico Ospedale Generale Regionale "F. Miulli"
Acquaviva delle Fonti, Italy Recruiting -
Azienda Socio Sanitaria Territoriale Degli Spedali Civili Di Brescia
Brescia, Italy Recruiting -
Univ. of Florence -Azienda Ospedaliero-Universitaria Careggi
Florence, Italy Recruiting -
Istituto Clinico Humanitas
Milan, Italy Recruiting -
IRCCS Ospedale San Raffaele
Milan, Italy Recruiting -
Istituto Europeo di Oncologia
Milan, Italy Recruiting -
Sacro Cuore Hospital
Negrar, Italy Recruiting -
IRCCS Ospedale Sacro Cuore Don Calabria
Negrar, Italy Recruiting -
San Maria della Misericordia Hospital
Perugia, Italy Recruiting -
Policlinico Universitario Campus Bio-Medico- Oncology Center
Roma, Italy Recruiting -
Fondazione Policlinico Universitario A. Gemelli - Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Roma, Italy Recruiting -
Azienda Ospedaliera Santa Maria di Terni
Terni, Italy Recruiting -
Azienda Ospedaliera Citta della Salute e della Scienza di Torino - Universita Di Torino - San Giovanni Battista
Torino, Italy Recruiting -
Stichting Catharina Ziekenhuis
Eindhoven, Netherlands Recruiting -
University Medical Center Groningen
Groningen, Netherlands Recruiting -
Radboudumc - Radboud University Medical Center Nijmegen
Nijmegen, Netherlands Recruiting -
Radiotherapiegroep Arnhem
Nijmegen, Netherlands Recruiting -
Wojewodzkie Wielospecjalistyczne Centrum Onkologii i Traumatologii im. M. Kopernika w Lodzi
Lodz, Poland Recruiting -
Kliniki Neuroradiochirurgii Sp. z o.o.-Radomskie Centrum Onkologii
Radom, Poland Recruiting -
The Institute Of Oncology
Ljubljana, Slovenia Recruiting -
ICO Badalona - Hospital Germans Trias i Pujol (Institut Catala D'Oncologia)
Badalona, Spain Recruiting -
Hospital Universitari Vall d'Hebron -Vall d'Hebron Institut Oncologia
Barcelona, Spain Recruiting -
Hospital De La Santa Creu I Sant Pau
Barcelona, Spain Recruiting -
Hospital General Universitario Santa Lucia
Cartagena, Spain Recruiting -
Hospital Universitario Reina Sofia
Córdoba, Spain Recruiting -
Hospital Universitario Ramon y Cajal
Madrid, Spain Recruiting -
Hospital Universitario La Paz
Madrid, Spain Recruiting -
Hospitales HM Sanchinarro-CIOCC
Madrid, Spain Recruiting -
Hospital Universitario de La Princesa
Madrid, Spain Recruiting -
Hospital Universitario de Salamanca (430)
Salamanca, Spain Recruiting -
Hospital Consorci Sanitari De Terrassa
Terrassa, Spain Recruiting -
Hospital Clinico Universitario De Valencia
Valencia, Spain Recruiting
+27 more sites. See ClinicalTrials.gov for the full list.
Study contacts
- Study coordinator: Eortc Hq
- Email: 1811@eortc.org
- Phone: +32 2 774 1611
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.