Collecting real-world data on cancer patients treated with radiotherapy in Europe
E²-RADIatE: EORTC-ESTRO RADiotherapy InfrAstrucTure for Europe
This study is collecting information from cancer patients receiving radiotherapy in Europe to see how well this treatment works alongside other therapies.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 2000 (estimated) |
| Ages | 12 Years and up |
| Sex | All |
| Sponsor | European Organisation for Research and Treatment of Cancer - EORTC Research network |
| Drugs / interventions | radiation |
| Locations | 77 sites (Graz and 76 other locations) |
| Trial ID | NCT03818503 on ClinicalTrials.gov |
What this trial studies
This observational study aims to gather real-world data from cancer patients who are undergoing radiotherapy. It focuses on understanding the role of radiation oncology within a multidisciplinary treatment approach. The study is non-interventional and will include multiple cohorts of patients, ensuring a comprehensive analysis of treatment outcomes. Participants will be monitored over time to provide valuable insights into the effectiveness of radiotherapy in cancer care.
Who should consider this trial
Good fit: Ideal candidates include patients aged 12 years and older with pathologically confirmed cancer who are planned to receive radiotherapy.
Not a fit: Patients who do not have a confirmed cancer diagnosis or are not planned for radiotherapy will not benefit from this study.
Why it matters
Potential benefit: If successful, this study could enhance the understanding of radiotherapy's impact on cancer treatment and improve patient outcomes.
How similar studies have performed: Other studies collecting real-world data in oncology have shown success in improving treatment protocols and patient outcomes, indicating that this approach is promising.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Pathologically confirmed cancer. * Written informed consent for E²-RADIatE according to applicable legal and ethical requirements * Planned use of radiotherapy * Eligibility of the patient confirmed for at least one cohort confirmed * Patients of 12 years and older
Where this trial is running
Graz and 76 other locations
- Medical University of Graz - Radio-oncology — Graz, Austria (Recruiting)
- Ordensklinikum Linz-Barmherzige Schwestern — Linz, Austria (Recruiting)
- Universitaetskliniken der Uni Wien - Universitaetsklinikum Wien - AKH unikliniken — Vienna, Austria (Recruiting)
- Onze Lieve Vrouw Ziekenhuis — Aalst, Belgium (Suspended)
- Cliniques Universitaires Saint-Luc — Brussels, Belgium (Recruiting)
- Institut Jules Bordet — Brussels, Belgium (Recruiting)
- Universitair Ziekenhuis Gent — Ghent, Belgium (Recruiting)
- AZ Sint-Lucas & Volkskliniek — Ghent, Belgium (Recruiting)
- AZ Groeninge Kortrijk - Campus Kennedylaan — Kortrijk, Belgium (Recruiting)
- U.Z. Leuven - Campus Gasthuisberg — Leuven, Belgium (Suspended)
- C.H.U. Sart-Tilman — Liège, Belgium (Suspended)
- CHU Site Sainte-Elisabeth-UCL Namur — Namur, Belgium (Suspended)
- AZ Turnhout - Campus Sint Elisabeth — Turnhout, Belgium (Recruiting)
- GasthuisZusters Antwerpen - Sint-Augustinus — Wilrijk, Belgium (Recruiting)
- University Hospital Hradec Kralove — Hradec Králové, Czechia (Recruiting)
- Clinique Pasteur-Lanroze (1174) — Brest, France (Suspended)
- Universitaetsklinikum Aachen AOR - Medizinische Fakultaet der RWTH — Aachen, Germany (Suspended)
- Klinikum Bayreuth Gmbh — Bayreuth, Germany (Suspended)
- Universitaetsklinikum Carl Gustav Carus — Dresden, Germany (Recruiting)
- Kliniken Maria Hilf GmbH — Mönchengladbach, Germany (Recruiting)
- Ludwig-Maximilians-Universitaet Muenchen - Campus Grosshadern — München, Germany (Recruiting)
- St Luke Hospital & SLRON - SLRON - St. Luke'S Hospital Rathgar — Dublin, Ireland (Recruiting)
- Beacon Hospital — Dublin, Ireland (Recruiting)
- University Hospital Galway — Galway, Ireland (Recruiting)
- Sheba Medical Center Tel Hashomer — Ramat Gan, Israel (Recruiting)
- Ente Ecclesiastico Ospedale Generale Regionale "F. Miulli" — Acquaviva delle Fonti, Italy (Recruiting)
- USL Toscana South East, Ospedale S. Donato — Arezzo, Italy (Suspended)
- Azienda Socio Sanitaria Territoriale Degli Spedali Civili Di Brescia — Brescia, Italy (Recruiting)
- Univ. of Florence -Azienda Ospedaliero-Universitaria Careggi — Florence, Italy (Recruiting)
- Istituto Clinico Humanitas — Milan, Italy (Recruiting)
- IRCCS Ospedale San Raffaele — Milan, Italy (Recruiting)
- Istituto Europeo di Oncologia — Milan, Italy (Recruiting)
- Sacro Cuore Hospital — Negrar, Italy (Recruiting)
- IRCCS Ospedale Sacro Cuore Don Calabria — Negrar, Italy (Recruiting)
- Istituti Clinici Scientifici Maugeri — Pavia, Italy (Suspended)
- Centro Nazionale di Adroterapia Oncoloica par il trattamento dei tumori — Pavia, Italy (Suspended)
- San Maria della Misericordia Hospital — Perugia, Italy (Recruiting)
- Policlinico Universitario Campus Bio-Medico- Oncology Center — Roma, Italy (Recruiting)
- Fondazione Policlinico Universitario A. Gemelli - Fondazione Policlinico Universitario Agostino Gemelli IRCCS — Roma, Italy (Recruiting)
- Azienda Ospedaliera Santa Maria di Terni — Terni, Italy (Recruiting)
- Azienda Ospedaliera Citta della Salute e della Scienza di Torino - Universita Di Torino - San Giovanni Battista — Torino, Italy (Recruiting)
- Stichting Catharina Ziekenhuis — Eindhoven, Netherlands (Recruiting)
- University Medical Center Groningen — Groningen, Netherlands (Recruiting)
- Radboudumc - Radboud University Medical Center Nijmegen — Nijmegen, Netherlands (Recruiting)
- Radiotherapiegroep Arnhem — Nijmegen, Netherlands (Recruiting)
- Wojewodzkie Wielospecjalistyczne Centrum Onkologii i Traumatologii im. M. Kopernika w Lodzi — Lodz, Poland (Recruiting)
- Kliniki Neuroradiochirurgii Sp. z o.o.-Radomskie Centrum Onkologii — Radom, Poland (Recruiting)
- Maria Sklodowska-Curie Memorial Cancer Centre - Maria Sklodowska-Curie National Research Institute of Oncology — Warsaw, Poland (Suspended)
- The Institute Of Oncology — Ljubljana, Slovenia (Recruiting)
- ICO Badalona - Hospital Germans Trias i Pujol (Institut Catala D'Oncologia) — Badalona, Spain (Recruiting)
+27 more sites — see ClinicalTrials.gov for the full list.
Study contacts
- Study coordinator: Eortc Hq
- Email: 1811@eortc.org
- Phone: +32 2 774 1611
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.