Collecting clinical outcomes for deep brain stimulation in movement disorders
Clinical Outcomes for Deep Brain Stimulation for Parkinson Disease, Tremor, and Dystonia
This study is tracking the experiences of people with movement disorders like Parkinson's disease who are getting deep brain stimulation to see how well it works and what risks it might have over time.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 1000 (estimated) |
| Sex | All |
| Sponsor | Washington University School of Medicine Academic / other |
| Locations | 1 site (St Louis, Missouri) |
| Trial ID | NCT03992625 on ClinicalTrials.gov |
What this trial studies
This observational study aims to longitudinally collect and analyze clinical outcomes of patients undergoing deep brain stimulation for movement disorders such as Parkinson's disease, essential tremor, and dystonia. The study will track risks, benefits, and complications associated with the treatment, allowing for retrospective comparisons over time. By gathering comprehensive data, the research seeks to enhance understanding of the effectiveness and safety of deep brain stimulation in these conditions.
Who should consider this trial
Good fit: Ideal candidates include individuals with levodopa-responsive Parkinson's disease, medically refractory essential tremor, or medically refractory dystonia.
Not a fit: Patients with dementia or structural abnormalities that prevent intracranial surgery may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could provide valuable insights into the long-term effects and safety of deep brain stimulation, potentially improving treatment strategies for patients with movement disorders.
How similar studies have performed: Other studies have shown success with similar approaches in evaluating deep brain stimulation, indicating a foundation for this research.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Levodopa responsive Parkinson disease OR * Medically refractory Essential Tremor OR * Medically refractory Dystonia Exclusion Criteria: * Dementia (Mattis Dementia Rating Scale \<130) * Structural abnormalities precluding intracranial surgery
Where this trial is running
St Louis, Missouri
- Washington University in St Louis — St Louis, Missouri, United States (Recruiting)
Study contacts
- Principal investigator: Mwiza Ushe, M.D. — Washington University School of Medicine
- Study coordinator: Mwiza Ushe, M.D.
- Email: ushem@wustl.edu
- Phone: 3143625262
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.