Collecting blood and tissue samples from patients with gastrointestinal cancer
Acquisition of Data, Blood, and Tumor Tissue Samples From Patients With Gastrointestinal Cancer
This study is collecting blood and tissue samples from people with gastrointestinal cancers to see how their immune system and gut bacteria affect the disease and to help improve future treatments.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 550 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | National Institutes of Health Clinical Center (CC) NIH |
| Drugs / interventions | CAR-T, chemotherapy, immunotherapy |
| Locations | 1 site (Bethesda, Maryland) |
| Trial ID | NCT01313442 on ClinicalTrials.gov |
What this trial studies
This study aims to gather blood and tumor tissue samples from individuals diagnosed with gastrointestinal cancers, such as throat, stomach, gallbladder, liver, pancreatic, or colon cancer. The objective is to analyze the immune system's response to these cancers and understand the role of gut microbiota in cancer progression. Participants will undergo a screening process and provide baseline samples during one to four visits to the National Institutes of Health Clinical Center. The findings may help inform future immunotherapy approaches and improve treatment strategies.
Who should consider this trial
Good fit: Ideal candidates are individuals aged 18 and older who have been diagnosed with gastrointestinal cancers and are scheduled for treatment at the National Institutes of Health.
Not a fit: Patients who do not have a diagnosis of gastrointestinal cancer or are under 18 years of age may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could enhance our understanding of immune responses in gastrointestinal cancers and lead to more effective treatment options.
How similar studies have performed: Other studies have shown promise in understanding immune responses in cancer, suggesting that this approach could yield valuable insights.
Eligibility criteria
Show full inclusion / exclusion criteria
* INCLUSION CRITERIA: * Individuals 18 years of age and older * Individuals with a diagnosis of cancer * Individuals must be able to understand and willing to sign a written informed consent document EXCLUSION CRITERIA: -None
Where this trial is running
Bethesda, Maryland
- National Institutes of Health Clinical Center — Bethesda, Maryland, United States (Recruiting)
Study contacts
- Principal investigator: Tim F Greten, M.D. — National Cancer Institute (NCI)
- Study coordinator: Stephanie N Hicks
- Email: hickssn2@nih.gov
- Phone: (240) 760-6159
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.