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Clinical trial Recruiting at 3 sites Observational Ages 18 and up

Collaborative effort to improve care for patients with cardiogenic shock

Official title: Multi-center Collaborative to Enhance Quality and Outcomes in the Management of Cardiogenic Shock

Run by University of Utah · NCT05185492 · Data updated 2026-11-12

This study is trying to gather information on how to better care for patients with cardiogenic shock caused by heart problems to help improve their treatment and outcomes.

Quick facts

Study typeObservational
Ages18 Years and up
SexAll
Enrollment500 (estimated)
SponsorUniversity of Utah
Academic / other
Locations3 sites (Weston, Florida and 2 other locations)
StatusRecruiting
StartedMay 25, 2022
Main results expectedDecember 31, 2027
Study endsDecember 31, 2027
Registry record updatedMarch 20, 2026
Trial IDNCT05185492 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates include patients diagnosed with cardiogenic shock due to acute myocardial infarction or acute decompensated heart failure.

Probably not a fit

Patients whose shock is not primarily cardiac in origin, such as those with septic or hemorrhagic shock, may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This international prospective registry aims to enhance understanding of the management and outcomes of patients experiencing cardiogenic shock across four high-volume care centers. By collecting comprehensive data on clinical courses and outcomes, the study seeks to identify factors associated with adverse outcomes and inform future clinical practices. The registry will focus on patients with cardiogenic shock stemming from acute myocardial infarction and acute decompensated heart failure, utilizing a standardized approach to care. The findings may serve as a blueprint for future clinical trials and improve treatment protocols.

Why it matters

Potential benefit: If successful, this study could lead to improved management strategies and better outcomes for patients suffering from cardiogenic shock.

How similar studies have gone: While there have been various studies on cardiogenic shock, this collaborative approach is novel and aims to fill gaps left by previous research.

Who can join: the full rules

Show full inclusion / exclusion criteria 
Inclusion Criteria:

* Primary diagnosis of cardiogenic shock at time of index evaluation; including acute myocardial infarction- and acute decompensated heart failure-cardiogenic shock phenotypes
* Patients with cardiac arrest complicating cardiogenic shock and those with massive pulmonary embolism with right ventricular cardiogenic shock will also be eligible for the registry

Exclusion Criteria:

* Patients with shock not due to primary cardiac etiology will be excluded. These include septic, hemorrhagic, and anaphylactic shock.

Where it's running

  • Cleveland Clinic Florida
    Weston, Florida, United States     Recruiting
  • Inova Heart and Vascular Institute
    Falls Church, Virginia, United States     Recruiting
  • University of Toronto
    Toronto, Ontario, Canada     Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
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Cardiogenic Shock 75Acute Myocardial Infarction 46University of Utah 695
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.