Cognitive improvement program using a serious game for multiple sclerosis patients

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study evaluates the effectiveness of a cognitive remediation program that utilizes a serious game to enhance information processing speed and episodic memory learning in patients with multiple sclerosis. Cognitive impairments are common in these patients, affecting their daily lives and quality of life. The program aims to provide a novel approach to address these cognitive deficits, which are often overlooked in traditional treatment plans. Participants will engage in the serious game alongside their usual care to assess improvements in cognitive function.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Relapsing-remitting or progressive multiple sclerosis people defined according to Mc Donald's criteria revised in 2005
* Age between ≥ 18 and ≤ 65 years old
* Cognitive complaint, with at least one deficient score at the initial neuropsychological examination (\<5th percentile of the reference group), one of the scores of which concerns at least one BICAMS test
* Have not had a definite relapse for at least 6 weeks
* Be at least 4 weeks away from a corticosteroid bolus
* Lack of neuroleptic treatment
* Patient with an Internet connection
* Signed informed consent

Exclusion Criteria:

* Severe cognitive deficit defined by obtaining a deficit score in more than six cognitive processes at the initial neuropsychological assessment.
* Neuropsychological care
* Inability to receive oral and written information
* Inability to use the software (due in particular to motor and / or sensory difficulties),
* Neurological or psychiatric comorbidity, other than MS and anxiodepressive syndrome
* Patient with severe anxiodepressive syndrome (BDI\> 27)
* Participation in an interventional study on cognitive functions
* Patient under legal protection, guardianship or curatorship
* Pregnant or breastfeeding women

Where it's running

• CH Arras
  Arras, Hauts-de-France, France Recruiting
• Ch Lens
  Lens, Hauts-de-France, France Recruiting
• Chru
  Lille, Hauts-de-France, France Recruiting
• Saint Vincent hospital
  Lille, Hauts-de-France, France Recruiting
• Saint-Philibert hospital
  Lomme, Nord, France Recruiting
• Charles Nicolle Hospital
  Rouen, Normandy, France Recruiting

Study contacts

• Principal investigator: Bruno Lenne — Hôpital Saint-Vincent de Paul
• Study coordinator: Amélie Lausiaux, MD, PhD
• Email: lansiaux.amelie@ghicl.net
• Phone: 03.20.22.52.69

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.