Coffee after spinal anesthesia for cesarean to reduce headache
The Effect of Postoperative Coffee Consumption on Postdural Puncture Headache and Analgesic Use in Women Undergoing Cesarean Section With Spinal Anesthesia: A Randomized Controlled Trial
NA · Hacettepe University · NCT07410741
This trial tests whether drinking coffee after a cesarean delivery with spinal anesthesia can reduce postdural puncture headache and the need for pain medicines in women.
Quick facts
| Phase | NA |
|---|---|
| Study type | Interventional |
| Enrollment | 82 (estimated) |
| Ages | 18 Years and up |
| Sex | Female |
| Sponsor | Hacettepe University (other) |
| Locations | 1 site (Ankara, Ankara) |
| Trial ID | NCT07410741 on ClinicalTrials.gov |
What this trial studies
Researchers at Hacettepe University will enroll women having cesarean delivery with spinal (spinal) anesthesia and offer postoperative oral coffee beginning at six hours after surgery. Participants who consume coffee will be compared with those who do not on rates of postdural puncture headache and postoperative analgesic use. Headache occurrence, severity, and pain medication consumption will be recorded in the postoperative period. The goal is to find a simple, low-cost, noninvasive approach that might reduce PDPH and decrease reliance on invasive treatments like epidural blood patching.
Who should consider this trial
Good fit: Women aged 18 or older undergoing cesarean section under spinal anesthesia who can read and communicate in Turkish, start oral intake six hours after surgery, and tolerate coffee are ideal candidates.
Not a fit: Patients with chronic headache disorders, emergency cesarean, conversion to general anesthesia, delayed postoperative oral intake, high-risk pregnancy, postoperative smoking, or intolerance to caffeine are unlikely to benefit.
Why it matters
Potential benefit: If successful, this could provide a simple, low-cost way to reduce postdural puncture headaches and lower the need for stronger pain medicines or invasive procedures.
How similar studies have performed: Some prior reports suggest caffeine can relieve PDPH through cerebral vasoconstriction, but results have been mixed and no definitive prevention approach has been established.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Ability to read, understand, and communicate in Turkish * Age ≥ 18 years * Undergoing cesarean section under spinal anesthesia * Spinal anesthesia administered in the sitting position * Initiation of oral intake at postoperative hour 6 * No history of physiological discomfort related to coffee consumption based on prior experience (e.g., insomnia, palpitations, headache) * Ability to understand the study procedures and communicate adequately to provide informed consent Exclusion Criteria: * Patients undergoing emergency cesarean section * Patients with a history of migraine or other types of chronic headache disorders * Patients in whom spinal anesthesia was converted to general anesthesia. * Patients whose oral intake was postponed for any reason in the postoperative period. * Patients with high-risk pregnancies. * Use of caffeine-containing analgesic medications during the postoperative period. * Postoperative cigarette smoking.
Where this trial is running
Ankara, Ankara
- Ankara Bilkent City Hospital — Ankara, Ankara, Turkey (Türkiye) (RECRUITING)
Study contacts
- Study coordinator: Simay Soyer Icbudak, PhD Candidate
- Email: simay.soyer@hacettepe.edu.tr
- Phone: +90 5326029045
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Postdural Puncture Headache, Post-Dural Puncture Headache, spinal anesthesia, caffeine, cesarean section, coffee