Clinical trial Recruiting at 1 site Interventional Ages 15 to 25

Circuit breathing for quitting e-cigarettes among youth

Official title: Acute Effects of Circuit Breathing Exercise on Smoking Cessation and Respiratory Function Among Youth E-Cigarette Users

Run by Chulalongkorn University · NCT07886099 · Data updated 2026-11-12

A small study tests whether a circuit breathing routine helps young e-cigarette users reduce withdrawal symptoms and improve breathing-related measures.

Quick facts

Study typeInterventional
Ages15 Years to 25 Years
SexAll
Enrollment20 (estimated)
SponsorChulalongkorn University
Academic / other
Locations1 site (Bangkok, Bangkok)
StatusRecruiting
StartedAugust 15, 2026
Main results expectedOctober 15, 2026
Study endsOctober 30, 2026
Registry record updatedOctober 21, 2026
Trial IDNCT07886099 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates are youth aged 15–25 who regularly use e-cigarettes (at least weekly or 10+ puffs daily) and are not physically active, with no major cardiovascular or respiratory diseases.

Probably not a fit

Individuals with cardiovascular or chronic respiratory conditions, or those who do not tolerate breathing exercises, may not benefit from this approach.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This randomized crossover study compares three breathing conditions—circuit breathing, diaphragmatic breathing, and normal breathing—in 20 youth e-cigarette users aged 15 to 25. Each participant experiences all conditions with at least one week between sessions to measure acute effects on nicotine withdrawal, dependence, heart rate, blood pressure, PNIF, and FeNO. The trial is conducted at Chulalongkorn University in Bangkok and does not involve a traditional drug treatment. Researchers will analyze which breathing technique most favorably influences withdrawal and respiratory parameters in the short term.

Why it matters

Potential benefit: If successful, circuit breathing could offer a simple, non-drug method to help youth manage withdrawal and improve respiratory measures during cessation efforts.

How similar studies have gone: Prior breathing-based interventions have shown short-term benefits for breath control and withdrawal symptoms in various populations, but this exact circuit breathing approach in youth e-cigarette users is novel.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Male or female aged 15-25 years.
* Regular e-cigarette use for at least six months and current e-cigarette use, defined as use on at least one day per week or at least 10 puffs per day during the past 30 days.
* Not regularly physically active, defined as exercising fewer than two times per week during the preceding six months.
* Able to understand instructions, communicate effectively, and cooperate with the research procedures.
* No history of cardiovascular disease or respiratory disease, such as asthma or chronic obstructive pulmonary disease.
* No uncontrolled hypertension. Participants with controlled hypertension must have resting blood pressure ≤140/90 mmHg.
* Able to move independently without assistance or assistive devices.
* Willing to participate and provide informed consent.
* For participants younger than 18 years, consent from a parent or legally authorized representative is required.

Exclusion Criteria:

* Development of an illness, injury, or other circumstance that prevents continued participation.
* Withdrawal of consent or unwillingness to continue participation.
* Current use of illicit drugs or other tobacco/nicotine products, including conventional cigarettes, shisha/hookah, roll-your-own tobacco, or other nicotine-containing products.

Where it's running

  • Faculty of Sports Science, Chulalongkorn University
    Bangkok, Bangkok, Thailand
    Recruiting

Study contacts

Similar studies

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How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.