Checks how well the Figure-of-Eight Walk and Weight-Bearing Lunge tests measure movement in adults with hemophilia
Official title: Validity and Reliability of the Figure-eight Walking Test and Weight-Bearing Lunge Test in Adult Patients With Hemophilia.
Run by Yuzuncu Yil University · NCT07851922 · Data updated 2026-11-12
This observational study tests two movement tests to see if they reliably reflect mobility in adults with hemophilia who have a history of joint bleeding.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years to 65 Years |
| Sex | Men only |
| Enrollment | 36 (estimated) |
| Sponsor | Yuzuncu Yil University Academic / other |
| Locations | 1 site (Van) |
| Status | Recruiting |
| Started | August 30, 2026 |
| Main results expected | October 15, 2026 |
| Study ends | October 15, 2026 |
| Registry record updated | October 1, 2026 |
| Trial ID | NCT07851922 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Adults 18-65 with hemophilia A, any clinical severity, and a history of knee or ankle joint bleeding who can walk at least 20 meters without assistance.
✕Probably not a fit
People who cannot walk independently, have active joint bleeding, or have other conditions affecting balance may not benefit from these tests.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
The study evaluates the validity and reliability of the Figure-of-Eight Walk Test and the Weight-Bearing Lunge Test in adults with hemophilia. Participants are adults aged 18-65 with varying severities of hemophilia A and a history of knee or ankle bleeding. The analysis focuses on how consistently these tests measure functional mobility and joint impact, informing their use in clinical assessment and rehabilitation. No interventions are described beyond the administration of the tests, and eligibility requires independent walking ability and absence of recent major surgery or active joint bleeding. Results will help determine whether these tests are appropriate outcome measures for mobility in this population.
Why it matters
Potential benefit: If valid and reliable, these tests could provide simple, low-cost tools to monitor mobility and rehabilitation progress in people with hemophilia.
How similar studies have gone: Similar functional tests have shown usefulness in other populations, supporting potential value but specific validation in hemophilia is limited.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * a diagnosis of hemophilia A * severe, moderate or mild clinical severity of hemophilia * a history of bleeding in at least one knee or ankle joint * being aged 18-65 * the ability to walk 20 meters independently without a cane or crutches Exclusion Criteria: * inability to stand unsupported; presence of an orthopaedic, neurological, and/or psychiatric condition affecting balance or physical performance * visual impairment * inhibitor positivity * inability to bear weight through the lower extremities * major lower-extremity surgery within the previous 6 months * haemarthrosis within the previous 2 weeks.
Where it's running
-
Van Yuzuncu Yil University
Van, Turkey (Türkiye) Recruiting
Study contacts
- Study coordinator: Necati Muhammed TAT, Assistant Professor
- Email: necatimuhammedtat@yyu.edu.tr
- Phone: +905075083347
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
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Personalized Hemophilia Care Through Telemedicine and Adherence Monitoring
This study tests a telemedicine-based program to closely monitor bleeding, ensure patients stick to their treatment plan, and personalize care for adults with hemophilia who use a smartphone.
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Multimodal Telerehabilitation vs Face-to-Face Care for Adults with Hemophilia and Chronic Pain
This trial tests whether a 6-week telerehabilitation program combining pain education and therapeutic exercise works as well as in-person care for adults with hemophilia and chronic pain.
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PCC treatment for hemophilia A patients with inhibitors
This trial tests whether giving prothrombin complex concentrate (PCC) during bleeding episodes can stop bleeds in people aged 12–65 with hemophilia A who have inhibitors.
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This study tests whether fitusiran given as prophylaxis can reduce bleeding in boys aged 1 to under 12 with severe hemophilia A or B, with or without inhibitors.
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This project will collect clinical data and blood/bone marrow samples from people having hematopoietic stem cell transplants on the Qinghai‑Tibet Plateau to see how high altitude affects transplant outcomes and recovery.
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Monitoring anti‑TFPI antibodies in adult men with severe hemophilia
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.