Checking if breaking up sitting with aerobic or sprint biking changes post-meal blood sugar and fat use
Official title: Postprandial Cardiometabolic Effects of Interrupting Sedentary Behavior With Exercise of Varying Intensity in Healthy Overweight Adults
Run by Hacettepe University · NCT07229963 · Data updated 2026-11-12
This study tests whether short bouts of aerobic or sprint cycling breaks taken during the post-meal period can improve blood sugar, insulin, inflammation, and blood pressure in overweight adults who sit a lot.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 30 Years to 45 Years |
| Sex | All |
| Enrollment | 18 (estimated) |
| Sponsor | Hacettepe University Academic / other |
| Locations | 1 site (Ankara, Beytepe) |
| Status | Recruiting |
| Started | September 1, 2026 |
| Main results expected | November 20, 2026 |
| Study ends | December 15, 2026 |
| Registry record updated | September 24, 2026 |
| Trial ID | NCT07229963 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Inactive adults with BMI 25–29.9 kg/m2 who sit for most of the day and have regular menstrual cycles (for female participants) and who have medical clearance to participate.
✕Probably not a fit
Individuals who are physically active, have BMI outside 25–29.9, have significant medical conditions limiting exercise, or have uncontrolled metabolic or cardiovascular risk factors may not benefit from these interventions.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
The trial compares two interruption strategies—aerobic exercise breaks and sprint interval breaks—against a sedentary period to see how each affects postprandial glucose, insulin, CRP, and blood pressure, as well as fat and carbohydrate oxidation. It targets overweight adults who are physically inactive and have high sedentary time. The study uses structured interventions performed during the postprandial window to determine which approach best improves cardiometabolic markers and substrate utilization. It builds on evidence that interrupting sitting with activity can improve metabolic responses and explores whether sprint intervals offer additional benefits. The investigation is conducted at a single institution in Ankara, Turkey, led by Hacettepe University.
Why it matters
Potential benefit: If successful, breaking up sedentary time with specific short exercise bouts could reduce post-meal cardiometabolic risk factors in overweight adults.
How similar studies have gone: Prior studies show that interrupting sedentary time with aerobic activity or sprint exercise can improve postprandial metabolic responses, though direct comparisons of the two approaches are limited.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria * Being physically inactive (not doing at least 150 minutes/week of structured exercise). * Being sedentary (having a daily sedentary time/day for \>7 hours). * Having a BMI between 25 and 29.9 kg/m2. * Having a history of regular menstrual cycles for female participants. * Having medical examination approval. Exclusion Criteria * Taking any acute or chronic medication or supplement that may affect metabolism. * Having an acute or chronic illness that limits exercise (musculoskeletal problems, cardiovascular disorders, respiratory problems, etc.). * Consuming tobacco products. * Meeting 3 or more of the metabolic syndrome criteria (waist circumference of 102 cm or more in men, 88 cm or more in women, triglyceride level of 150 mg/dL or higher, HDL cholesterol level below 40 mg/dL in men and 50 mg/dL in women, blood pressure of 130/85 mmHg or higher, fasting blood glucose level of 100 mg/dL (5.6 mg/L) or higher).
Where it's running
-
Hacettepe Sports Science Faculty, Hacettepe Beytepe Clinic
Ankara, Beytepe, Turkey (Türkiye) Recruiting
Study contacts
- Principal investigator: Şükran Nazan Koşar, Professor — Hacettepe University
- Study coordinator: Hikmet Sercan Toprakoğlu
- Email: sercantprkgl@gmail.com
- Phone: +905369792652
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
-
Pre-run Supplements on a 5K Run in Runners
This study tests whether caffeine, L-citrulline, or an exogenous ketone taken before a 5 km treadmill run change how efficiently runners move, how their heart and lungs respond, and how they feel while running.
-
Blood-based markers linked to aerobic (VO₂max/VO₂peak) fitness
This project will try a blood test to see if it can predict VO₂max/VO₂peak in adults who can safely complete maximal exercise testing.
-
Exercise Self-Efficacy, Body Composition, and Activity in Men with Low Testosterone
This study tests how confident men on testosterone therapy are at staying active and whether that confidence links body fat and lean mass with how much they exercise.
-
Individualized pelvic floor rehab added to standard urotherapy and alarm therapy for kids with bedwetting
This trial tests whether adding personalized pelvic floor muscle training to standard alarm therapy helps reduce dry nights in children aged 5–18 with primary monosymptomatic nocturnal enuresis.
-
Core muscle function and balance in people with leg amputations
This study tests how leg amputation affects core muscles and balance by comparing muscle thickness on the amputated side, the intact side, and healthy people using ultrasound.
-
Aerobic Exercise and Massage for Painful Bladder Syndrome in Women
This study tests whether adding aerobic exercise and connective tissue massage to patient education helps reduce bladder pain and improve symptoms for women with bladder pain syndrome.
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.