Changes in airway bacteria after replacing artificial airways in critically ill children
Airway Microbiome Changes After Artificial Airway Exchange in Critically-ill Pediatric Patients.
Northwell Health · NCT06201130
This study looks at how changing artificial airways in critically ill children affects the bacteria in their lungs and whether it impacts their risk of infections.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 50 (estimated) |
| Ages | 0 Years to 18 Years |
| Sex | All |
| Sponsor | Northwell Health (other) |
| Locations | 1 site (Queens, New York) |
| Trial ID | NCT06201130 on ClinicalTrials.gov |
What this trial studies
This observational study examines the changes in the airway microbiome of critically ill pediatric patients who have artificial airways, such as tracheostomies and endotracheal tubes. It focuses on the impact of artificial airway exchange on microbial colonization and the potential risks of ventilator-associated infections. By analyzing bacterial growth and colonization patterns, the study aims to understand the relationship between airway management and infection rates in pediatric intensive care units. The methodology includes suctioning of artificial airways to collect samples for microbiome analysis.
Who should consider this trial
Good fit: Ideal candidates for this study are pediatric patients with tracheostomies or endotracheal tubes in the pediatric or neonatal intensive care units.
Not a fit: Patients who do not have artificial airways or are not in critical care settings may not receive any benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved management strategies for preventing infections in critically ill pediatric patients with artificial airways.
How similar studies have performed: While there is ongoing research in the area of airway microbiomes, this specific approach to studying changes after artificial airway exchange in pediatric patients is relatively novel.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * All patients with tracheostomies in the pediatric or neonatal intensive care unit * Patients with endotracheal tubes undergoing artificial airway exchange in the pediatric or neonatal intensive care unit Exclusion Criteria: * None
Where this trial is running
Queens, New York
- Cohen Children's Medical Center — Queens, New York, United States (RECRUITING)
Study contacts
- Study coordinator: Evin S Feldman, MD
- Email: efeldman4@northwell.edu
- Phone: (516) 562-3467
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Tracheostomy, Endotracheal Tube, Ventilator Associated Pneumonia, Tracheitis, Microbial Colonization, Pediatric Infectious Disease, Pediatrics