Cardiovascular history and hemodynamic problems after intubation in ICU
Official title: Impact of Cardiovascular History on the Incidence of Severe Hemodynamic Complications Following Intubation in Intensive Care Units
Run by University Hospital, Strasbourg, France · NCT07864259 · Data updated 2026-11-12
This study looks back at ICU patients to see if having cardiovascular disease makes severe blood pressure problems after intubation more likely.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 160 (estimated) |
| Sponsor | University Hospital, Strasbourg, France Academic / other |
| Locations | 1 site (Strasbourg) |
| Status | Recruiting |
| Started | January 13, 2026 |
| Main results expected | December 13, 2026 |
| Study ends | January 13, 2027 |
| Registry record updated | October 7, 2026 |
| Trial ID | NCT07864259 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Adults (18+) in the ICU who require intubation and have no documented opposition to data reuse, with a history of cardiovascular disease of interest or none.
✕Probably not a fit
Patients without cardiovascular disease or those who do not experience post-intubation hemodynamic instability may not see direct benefits from this analysis.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This is a retrospective, single-center observational study conducted in the ICU, examining adults who required intubation. It aims to determine whether a history of cardiovascular disease is associated with severe hemodynamic complications within 30 minutes after intubation. Severe complications include profound hypotension, starting or increasing norepinephrine, fluid resuscitation for instability, or cardiac arrest. Data are drawn from patients admitted to the ICU between January 1, 2024 and September 30, 2025, with consent for data reuse as required. The study does not specify an intervention and analyzes existing medical records to identify potential risk factors related to cardiovascular history.
Why it matters
Potential benefit: If successful, the findings could help clinicians anticipate and mitigate hemodynamic instability after intubation in ICU patients with cardiovascular disease.
How similar studies have gone: Previous observational work in critical care has identified cardiovascular risk factors as contributors to post-intubation instability, but this specific association in ICU intubations is less established and warrants investigation.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patient aged 18 years or older * Patient hospitalized in intensive care unit between 01/01/2024 and 30/09/2025 * Patient requiring intubation in intensive care unit * Absence of documented opposition to data reuse for research Exclusion Criteria: * Patient intubated for cardiac arrest * Patient intubated outside intensive care unit * Patient intubated under awake fiberoptic technique * Patient under legal protection (guardianship or curatorship)
Where it's running
-
Service de Médecine Intensive - Réanimation - CHU de Strasbourg - France
Strasbourg, France Recruiting
Study contacts
- Study coordinator: Max Guillot, MD
- Email: max.guillot@chru-strasbourg.fr
- Phone: 33 3 88 12 79 13
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.