Cardio or Conditioning Training With Breast Cancer

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This interventional study compares two exercise approaches in women with a history of breast cancer: resistance training with cardio versus resistance training with conditioning. The goal is to see if the conditioning approach yields similar improvements in body composition, muscle mass, and blood pressure as traditional cardio-based training. Participants are adults 20 to 89 who have completed breast cancer treatment (excluding those on active cytotoxic chemotherapy) and have prior guided resistance training experience. The trial is led by Allegheny Singer Research Institute at AHN Allegheny General Hospital and takes place in Pittsburgh, PA. Eligibility emphasizes safety for group resistance sessions and English literacy for consent.

Why it matters

Who can join: the full rules

Inclusion Criteria:

1. Age 20-89 years
2. Women prescribed exercise as a SOC
3. Women with a biopsy proven diagnosis of ductal carcinoma in situ (DCIS) or invasive carcinoma of the breast
4. Women must have undergone treatment for breast cancer, including one or more of the following: surgery, radiation therapy, chemotherapy, immunotherapy, or hormonal therapy. Women undergoing active chemotherapy are not allowed on study. Immunotherapy or targeted agent usage is allowed.
5. Women with \> 3 months of resistance training experience under expert guidance by a CSCS
6. Must be able to read and understand English and consent for themselves.

Exclusion Criteria:

1. Any current treatment with cytotoxic chemotherapy for breast cancer
2. Inability to safely engage in group sessions of resistance training as deemed by study PI
3. Severe arthritic, joint, cardiovascular, or musculoskeletal condition deemed by PI to be unsafe to engage in resistance training
4. Beta blocker or GLP-1 inhibitor medications
5. Pregnant women
6. Males

Where it's running

• AHN Allegheny General Hospital
  Pittsburgh, Pennsylvania, United States Recruiting

Study contacts

• Principal investigator: Colin Champ, MD, CSCS — AHN Radiation Oncology
• Study coordinator: Clinical Trials Contact
• Email: ctgov@ahn.org
• Phone: 412-330-6151

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.