Cancer-associated VTE: A follow-up study collecting biological samples
Official title: Establishment of a Patient-based Cohort : Cancer-related Venous Thromboembolic Disease.
Run by University Hospital, Brest · NCT06393764 · Data updated 2026-11-12
This study tests how often cancer patients who have had a VTE will experience more clots over time and gathers blood and urine samples to explore why it happens.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years to 80 Years |
| Sex | All |
| Enrollment | 150 (estimated) |
| Sponsor | University Hospital, Brest Academic / other |
| Locations | 1 site (Brest) |
| Status | Recruiting |
| Started | October 30, 2025 |
| Main results expected | October 2035 |
| Study ends | October 2035 |
| Registry record updated | June 15, 2026 |
| Trial ID | NCT06393764 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Adults with active cancer or undergoing cancer treatment who recently had a documented VTE and are able to consent.
✕Probably not a fit
Patients with very short life expectancy or those unable to participate in follow-up may not benefit from the study findings.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This is a prospective, single-center observational cohort study aimed at understanding the recurrence risk and underlying mechanisms of venous thromboembolism in cancer patients. Researchers will collect blood samples at study entry and at recurrence events to build a biobank for future analyses, and urine samples annually for up to five years. The study follows patients with active cancer or those undergoing cancer treatment who recently experienced VTE, to better characterize risks, biology, and prognosis in this high-risk population. Interventions are limited to biological sample collection; no experimental therapies are used. The findings may help refine risk stratification and future research in cancer-associated VTE.
Why it matters
Potential benefit: If successful, the study could improve understanding of VTE recurrence in cancer patients and support development of better prevention and monitoring strategies.
How similar studies have gone: Prior research has shown that cancer-associated VTE is clinically significant, and biobanking approaches have yielded insights in other studies, though the specific cohort design is somewhat unique.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patients aged 18 years and more. * Patients with active cancer or requiring cancer treatment at the time of their VTE episode * Patients with documented VTE less than 2 years old * Patients affiliated to the social security system * Patient who has signed a written informed consent Exclusion Criteria: * Patient under 18 * Refusal to participate * Incapacity to consent to the study * Patient under guardianship * Incapacity to communicate (comprehension disorder) * Life expectancy of less than 6 months
Where it's running
-
Brest University Hospital
Brest, France Recruiting
Study contacts
- Principal investigator: Françis Couturaud, Pr — CHU Brest
- Study coordinator: Françis Couturaud, Pr
- Email: francis.couturaud@chu-brest.fr
- Phone: +33298347348
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.