Can a wearable TENS device reduce chronic nausea symptoms?

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

The WINNER study is a single-center interventional trial evaluating a wearable transcutaneous electrical nerve stimulation device that targets the median nerve at the wrist. Adults with nausea lasting more than two months will use the EmeTerm device to see if it lowers the weekly frequency of moderate-to-severe nausea compared with a baseline period. Secondary outcomes include changes in nausea duration, vomiting frequency, anti-nausea medication use, and broader wellbeing measures such as appetite, sleep, mood, and quality of life. The device has FDA clearance for motion sickness- and pregnancy-related nausea. Participants will undergo baseline assessments and daily symptom tracking via online surveys during participation at The Ohio State University Wexner Medical Center.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Nausea present for more than 2 months. Age 18 years or older. Able to understand English. Receiving care at The Ohio State University. Able to complete online surveys using a smartphone or computer

Exclusion Criteria:

* Active treatment for cancer Current treatment for inflammatory bowel disease Cirrhosis End-stage renal disease Prior use of a wearable TENS unit for nausea Abdominal surgery within the previous 3 months Pregnancy (self-reported at enrollment) Current carpal tunnel syndrome Any contraindication to use of the EmeTerm device Inflammation, irritation, infection, ulceration, bleeding, open wounds, or other skin conditions near the wrist where the device is applied Presence of metallic implants in the body Head or facial injury within the previous 3 months Known brain tumor, meningitis, or stroke within the previous 3 months Cardiac pacemaker, implanted defibrillator, or other implanted metallic or electronic device History of seizures

Where it's running

• Ohio State University Wexner Medical Center
  Columbus, Ohio, United States Recruiting

Study contacts

• Principal investigator: Subhankar CHAKRABORTY, MD, Ph.D. — Ohio State University
• Study coordinator: SUBHANKAR CHAKRABORTY, M.D., Ph.D.
• Email: Subhankar.chakraborty@osumc.edu
• Phone: 614-293-6255'

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.