Calcitonin treatment for neuropathic pain after spinal cord injury
Official title: Effect of Early Calcitonin Therapy on Incidence and Severity of Neuropathic Pain After Spinal Cord Injury
Run by Tanta University · NCT05805683 · Data updated 2026-11-12
This study is testing if calcitonin can help reduce the pain that people experience after a spinal cord injury compared to a placebo.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 126 (estimated) |
| Sponsor | Tanta University Academic / other |
| Locations | 1 site (Tanta, Gharbia Governorate) |
| Status | Recruiting |
| Started | May 1, 2023 |
| Main results expected | May 1, 2027 |
| Study ends | May 1, 2028 |
| Registry record updated | May 14, 2026 |
| Trial ID | NCT05805683 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates include adults aged 18 and older who have sustained a spinal cord injury at any level and degree of completeness shortly after the trauma.
✕Probably not a fit
Patients who are currently taking anticonvulsants, have existing neuropathic pain, or have a history of allergic reactions to calcitonin may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This prospective randomized double-blinded study aims to evaluate the effects of early calcitonin treatment on the incidence and severity of neuropathic pain following spinal cord injury. The study will categorize pain into various types and assess how calcitonin, known for its effectiveness in managing acute pain in other conditions, can help in this context. Participants will be randomly assigned to receive either calcitonin or a placebo, allowing for a controlled comparison of outcomes.
Why it matters
Potential benefit: If successful, this treatment could significantly reduce the incidence and severity of neuropathic pain in patients with spinal cord injuries.
How similar studies have gone: Previous studies have shown calcitonin to be effective in managing acute pain in various conditions, suggesting potential for success in this novel application.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patients aged ≥18 years, with spinal cord injury at any level and any degree of completeness in the early stage of trauma. Exclusion Criteria: * Intake of anticonvulsants medications. * Evidence of neuropathic pain. * Evidence of previous allergic reaction to calcitonin. * Patients with renal, hepatic and cardiac dysfunction or neurological disorders . * brain damage or major trauma to extremities or abdomen.
Where it's running
-
Tanta University
Tanta, Gharbia Governorate, Egypt Recruiting
Study contacts
- Study coordinator: Osama M Rehab, MD
- Email: osamarehab@med.tanta.edu.eg
- Phone: 00201095210806
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.