Burdock root extract for people with high uric acid without gout
Official title: Multicentre, Double-blind, Randomized, Placebo-controlled Trial of Clinical Efficacy of Burdock Root Extract in Patients With Asymptomatic Hyperuricaemia
Run by Omnifarma LLC · NCT07002762 · Data updated 2026-11-12
This trial will test whether burdock root extract can lower uric acid levels in adults aged 35–65 who have asymptomatic hyperuricaemia.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 35 Years to 65 Years |
| Sex | All |
| Enrollment | 100 (estimated) |
| Sponsor | Omnifarma LLC Industry-sponsored |
| Locations | 1 site (Kyiv) |
| Status | Recruiting |
| Started | March 12, 2025 |
| Main results expected | September 30, 2025 |
| Study ends | September 30, 2025 |
| Registry record updated | July 30, 2025 |
| Trial ID | NCT07002762 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are adults aged 35–65 with laboratory-confirmed asymptomatic hyperuricaemia (women 360–540 μmol/L, men 420–540 μmol/L) who have no clinical signs of gout and are not taking other supplements or interfering medications.
✕Probably not a fit
People with active gout, recent antigout drug use, uric acid levels outside the specified ranges, pregnant or breastfeeding individuals, or those on contraindicated diuretics are unlikely to benefit from participation.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This is a multicentre, double-blind, randomized, placebo-controlled trial comparing burdock (Arctium lappa) root extract as a nutritional additive against placebo in adults with asymptomatic hyperuricaemia. Participants must be 35–65 years old with lab-confirmed serum uric acid 360–540 μmol/L for women and 420–540 μmol/L for men and have no clinical signs of gout. Key exclusions include active gout, recent antigout medication use, pregnancy or lactation, fever, and concurrent use of other nutritional additives or certain diuretics. The trial is sponsored by OMNIFARMA LLC with recruitment listed at the National Research Centre "Academician M. D. Strazhesko Institute of Cardiology" in Kyiv.
Why it matters
Potential benefit: If successful, this could offer an accessible, non-prescription option to help lower uric acid and potentially reduce progression to symptomatic gout.
How similar studies have gone: There is limited high-quality randomized trial evidence for burdock root in lowering uric acid, so this approach remains relatively novel and unproven in rigorous trials.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Hyperuricaemia confirmed by a laboratory, uric acid level from 360 to 540 μmol/L in women and from 420 to 540 μmol/L in men; * Age from 35 to 65 years at the baseline; * Patients examined by an experienced specialist not revealing any clinical evidences of gout or other somatic consequences of hyperuricaemia; * Not taking any other nutritional additives; * Women of reproductive age having negative pregnancy test at the baseline and at the end of the trial; * Not taking any diuretics, or their administration based on a regimen usual for a patient, without changes; * Not taking part in any other clinical trials; * Consent and voluntarily signed informed consent form for participation in the clinical trial. Exclusion Criteria: * Age \<35 or \>65 years; * Fever (above 36.8 оС); * Pregnancy and lactation; * Patients with any somatic evidences of hyperuricaemia including gout taking antigout drugs during or within 6 months before the trial; * Patients with mental disorders / taking antipsychotics or antidepressants; * Patients not giving (informed) consent to participate in the trial; * Patients causing doubts of the study doctor as to their motivation to comply with the trial; * Presence of any concomitant decompensated diseases or acute conditions able to influence results of the trial; * Alcohol abuse and drug addiction; * Changes in taking diuretics within a month before and during the trial; * Participation in any other clinical trial; * Taking any nutritional additives.
Where it's running
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State Institution "National Research Centre "Academician M. D. Strazhesko Institute of Cardiology
Kyiv, Ukraine Recruiting
Study contacts
- Study coordinator: Oleg V Kurchenko, MD
- Email: kurchenko@omnifarma.com.ua
- Phone: +380503319653
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.