Building a multiomic database using advanced imaging techniques
Advanced Imaging Holistic Omics Biobank
This study is trying to build a big database using advanced imaging techniques to see how different health information can help better understand and prevent diseases in adult patients.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 50000 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | IRCCS San Raffaele Academic / other |
| Locations | 1 site (Milan) |
| Trial ID | NCT06523270 on ClinicalTrials.gov |
What this trial studies
This observational study aims to create a large-scale multiomic database by enrolling adult patients undergoing advanced imaging studies, specifically using Photon Counting CT and 3T MRI. The study will collect imaging raw data, clinical, demographic, and laboratory test results, as well as genetic testing information when available. Patients will be followed annually to update their clinical and imaging data, allowing for a comprehensive analysis of the latent information derived from these advanced imaging modalities. The goal is to explore the potential of these 'opportunist features' in enhancing patient characterization and improving screening and prevention strategies.
Who should consider this trial
Good fit: Ideal candidates are adult patients over 18 years old who are scheduled for CT or MRI examinations at the IRCCS San Raffaele Hospital.
Not a fit: Patients who are unable to provide informed consent or are not undergoing the specified imaging examinations will not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved diagnostic and preventive strategies for various oncologic, neurologic, pulmonary, and cardiovascular disorders.
How similar studies have performed: While the approach of utilizing advanced imaging data for multiomic analysis is innovative, similar studies have shown promise in leveraging imaging data for enhanced patient characterization.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Adult subjects (\>18 y.o.) submitted to Computed Tomography (CT) using Photon Counting CT scanner (Neaotom Alpha, Siemens) and Magnetic Resonance (MRI) exams acquired with 3T scanner (MR 7700, Philips) for examination required for clinical practice or for clinical trials at the IRCCS San Raffaele Hospital who signe an Informed Consent authorizing data collection. Exclusion Criteria: * Absent informed consent signed
Where this trial is running
Milan
- IRCCS San Raffaele — Milan, Italy (Recruiting)
Study contacts
- Study coordinator: Antonio Esposito
- Email: esposito.antonio@hsr.it
- Phone: 0226436102
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.