Breathing and Suboccipital Release to Help Stroke Rehab
Official title: COMPARISON OF THE EFFECTS OF DEEP AND SLOW BREATHING EXERCISES AND SUBOCCIPITAL RELEASE, ADDED TO ROUTINE PHYSIOTHERAPY AND REHABILITATION, ON AUTONOMIC, MOTOR, AND COGNITIVE FUNCTIONS AND EMOTIONAL STATUS IN STROKE PATIENTS
Run by Ankara Yildirim Beyazıt University · NCT07725471 · Data updated 2026-11-12
This study tests whether adding deep, slow breathing and suboccipital relaxation to standard stroke rehab can improve autonomic function, movement, thinking, and mood.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years to 84 Years |
| Sex | All |
| Enrollment | 54 (estimated) |
| Sponsor | Ankara Yildirim Beyazıt University Academic / other |
| Locations | 1 site (Afyonkarahisar) |
| Status | Recruiting |
| Started | July 6, 2026 |
| Main results expected | September 1, 2027 |
| Study ends | September 30, 2027 |
| Registry record updated | July 24, 2026 |
| Trial ID | NCT07725471 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Adults aged 18–84 with a first-time stroke and unilateral hemiplegia, at least 3 months post-stroke, who can provide informed consent.
✕Probably not a fit
Patients with active respiratory disease, certain cardiac conditions, severe aphasia or cognitive impairment, or other major comorbidities may not benefit.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This interventional study will compare a breathing plus suboccipital relaxation program added to routine physiotherapy against routine rehabilitation alone in adults with a prior stroke. Participants will undergo deep, slow breathing exercises and suboccipital release in addition to standard care, with outcomes focused on autonomic regulation, motor function, cognitive performance, and emotional well-being. The rationale is that these techniques may enhance heart rate variability, balance, and sleep, potentially improving overall rehabilitation outcomes. The study builds on prior evidence of individual benefits from breathing exercises and suboccipital therapies, and aims to evaluate their combined effect in stroke rehab.
Why it matters
Potential benefit: If successful, patients may experience better autonomic control, improved balance and gait, sharper cognition, and reduced stress or mood symptoms.
How similar studies have gone: Prior studies show benefits of breathing exercises and suboccipital therapies individually; this study is novel in evaluating their combined effect in stroke rehabilitation.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * First-time diagnosis of stroke * Presence of unilateral hemiplegia due to ischemic or hemorrhagic stroke etiology * Presence of hemiparesis * At least 3 months post-stroke * Having signed the informed consent form * Aged between 18 and 84 years Exclusion Criteria: * Presence of active or chronic respiratory disease * Low heart rate (\<60 bpm) * Known cardiac conduction disorder * Symptomatic carotid or vertebrobasilar stenosis * Severe carotid or vertebrobasilar stenosis * Advanced liver, kidney, heart, or lung disease * Diagnosed depression * Pregnancy * Severe aphasia or cognitive impairment that may interfere with the informed consent process or study procedures * Malignant tumors or infectious diseases * Presence of a pacemaker or other implanted electrical device * Spasticity of grade 4 or higher according to the Modified Ashworth Scale in the upper and lower extremities * Brunnstrom Motor Staging below stage 3 in the upper and lower extremities * Failure to meet the inclusion criteria
Where it's running
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Afyonkarahisar Health Sciences University Health Practice and Research Center
Afyonkarahisar, Turkey (Türkiye) Recruiting
Study contacts
- Study coordinator: Zeynep Arikan
- Email: zeynepcikar61@gmail.com
- Phone: +905536655775
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.