Blood pressure changes during exercise and aortic stiffness in CKM syndrome
Official title: The Relationship Between Blood Pressure Response to Exercise Testing and Aortic Stiffness in Patients With Cardiovascular-Kidney-Metabolic Syndrome
Run by Karamanoğlu Mehmetbey University · NCT07737561 · Data updated 2026-11-12
This study tests whether blood pressure responses during a clinically indicated exercise test are linked to how stiff the aorta is in adults with CKM syndrome.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 80 (estimated) |
| Sponsor | Karamanoğlu Mehmetbey University Academic / other |
| Locations | 1 site (Karaman) |
| Status | Recruiting |
| Started | July 15, 2026 |
| Main results expected | September 30, 2026 |
| Study ends | January 1, 2027 |
| Registry record updated | July 30, 2026 |
| Trial ID | NCT07737561 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are adults with CKM syndrome who are referred for an exercise stress test and can safely perform the test.
✕Probably not a fit
Patients unable to perform an exercise stress test or without the specific CKM syndrome profile may not benefit from this observational analysis.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational study explores the relationship between how blood pressure rises during an exercise stress test and aortic stiffness in adults diagnosed with CKM syndrome. Participants are adults aged 18 and older with CKM syndrome who are referred for an exercise stress test as part of routine care. The study analyzes data from a clinically indicated exercise test to see if a high BP response corresponds to greater aortic stiffness, which could help identify cardiovascular risk patterns in CKM patients.
Why it matters
Potential benefit: If a link is found, clinicians may better stratify cardiovascular risk in CKM patients using exercise test BP responses and aortic stiffness measures.
How similar studies have gone: Previous work has linked exaggerated BP responses to adverse outcomes, but this study applies it specifically to CKM syndrome and its association with aortic stiffness.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Willing and able to provide written informed consent. * Aged 18 years or older. * Diagnosis of Cardiovascular-Kidney-Metabolic (CKM) syndrome. * Referred by a cardiologist for a clinically indicated exercise stress test as part of routine clinical care. * Able to perform an exercise stress test. Exclusion Criteria: * Physical disability or any medical condition that precludes performing an exercise stress test. * Diagnosis of major depressive disorder
Where it's running
-
Karaman Training and Research Hospital
Karaman, Turkey (Türkiye) Recruiting
Study contacts
- Study coordinator: Emine Tunç Süygün
- Email: fzteminetunc@gmail.com
- Phone: +90338 226 21 92
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.