Blood lipid and ceramide profiles in atrial fibrillation

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This is a prospective, multi-cohort observational study comparing peripheral blood lipidomic features and ceramide profiles in adults with atrial fibrillation to controls with cardiovascular disease but no AF. One cohort will undergo untargeted lipidomic profiling and another will have targeted ceramide assays. Participants are classified by Holter monitoring and clinical data, and samples are analyzed to explore associations with atrial fibrillation. The study is conducted at the First Affiliated Hospital of Xi’an Jiaotong University, without an interventional treatment. Findings could help clarify whether lipid and ceramide patterns are linked to AF pathophysiology.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Adults aged 18 years or older.
* Participants who are able to provide informed consent.
* Participants diagnosed with atrial fibrillation based on Holter monitoring, or control participants with other cardiovascular diseases and no documented atrial fibrillation.
* Participants with available peripheral blood samples for untargeted lipidomic profiling or targeted ceramide analysis.

Exclusion Criteria:

* Inability or unwillingness to provide informed consent.
* Missing key clinical information.
* Missing or poor-quality peripheral blood samples unsuitable for lipidomic or targeted ceramide analysis.
* Participants considered unsuitable for this study by the investigators.

Where it's running

• First Affiliated Hospital of Xian JiaotongUniversity
  Xi'an, Shaanxi, China Recruiting

Study contacts

• Study coordinator: Weiyan Zhang
• Email: zwhy19324@gmail.com
• Phone: 0086-13571200428

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.