BL1107 dosing for drying eye redness: finding the lowest effective amount

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This Phase 2 interventional study aims to identify the lowest effective concentration of BL1107 that achieves complete resolution of conjunctival hyperemia in adults with dry eye disease. Participants will be randomized to receive varying concentrations of BL1107 and will be masked to the specific concentration administered. The study focuses on those with bilateral conjunctival redness and excludes individuals with active ocular disease or those likely to wear contact lenses during participation. Lead sponsorship is by Bausch & Lomb Incorporated, with the single site located in Newport Beach, California. Outcomes will inform dosing strategies to optimize efficacy while minimizing exposure.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Documented diagnosis of dry eye disease
* Conjunctival hyperemia in both eyes, without clinical signs of infection or allergic conjunctivitis

Exclusion Criteria:

* Any active ocular disease
* Anticipated wearing of contact lenses during study

Additional criteria per protocol

Where it's running

• Site 101
  Newport Beach, California, United States Recruiting

Study contacts

• Study coordinator: Johnson Varughese
• Email: Johnson.Varughese@bausch.com
• Phone: 9089271162

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.