Biobank for patients with large vessel occlusion stroke

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This multicenter, ambispective cohort study collects and analyzes blood and thrombus samples from patients with acute ischemic stroke caused by large vessel occlusion. The study aims to establish a comprehensive multiomics biobank, which includes clinical, laboratory, imaging, and follow-up data from five stroke centers. By performing detailed analyses such as metabolomics, proteomics, and genomics, researchers seek to identify phenotypic differences and develop clinical prediction models to improve diagnosis and prognosis for these patients. The rich dataset will also facilitate further scientific inquiries related to stroke.

Why it matters

Who can join: the full rules

Inclusion Criteria:

1. Age over 18 years.
2. Patients with intracranial and extracranial large vessel occlusion ischemic stroke confirmed by cerebrovascular angiography.
3. Availability of complete clinical and follow-up information required for the study.
4. Availability of blood and/or thrombus biological samples.
5. Voluntary written informed consent signed by the patient or their family (1) For retrospectively enrolled patients, a "broad informed consent" was signed at the time of sample collection. Upon enrollment into the cohort, a follow-up phone call was made to confirm the informed consent.

(2) For prospectively enrolled patients, informed consent for this study was signed at the time of enrollment by the patient or their family.

Exclusion Criteria:

1. Patients for whom biological samples cannot be obtained;
2. Patients or their family members who refuse to sign the informed consent form.

Where it's running

• Baotou Central Hospital
  Baotou, Inner Mongolia, China Recruiting
• Affiliated Hospital of Shandong University of Traditional Chinese Medicine Hospital
  Jinan, Shandong, China Recruiting
• The First Affiliated Hospital of zhengzhou University
  Henan, Zhengzhou, China Recruiting
• Capital medical university of Beijing Tiantan Hospital
  Beijing, China Recruiting
• The First Affiliated Hospital of Shihezi University
  Wuhu, Anhui, China Not yet recruiting

Study contacts

• Study coordinator: Zhiyuan Feng, MD
• Email: fzyhhz1996@gmail.com
• Phone: 86+15801290121

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.