Bilevel erector spinae plane block vs pectoserratus block for pain relief after mastectomy

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This interventional study compares two ultrasound-guided regional anesthesia techniques—bilevel erector spinae plane block (ESPB) and pectoserratus block (PSPB)—for postoperative analgesia in women undergoing modified radical mastectomy with axillary dissection. Participants are adult female breast cancer patients, ASA II-III, aged 18–65, with BMI 20–35 kg/m2. Outcomes focus on analgesia quality, opioid consumption, recovery parameters, and potential side effects within the immediate postoperative period. The trial takes place at the National Cancer Institute, Cairo University, sponsored by the National Cancer Institute, Egypt. Data from this comparison could inform multimodal analgesia strategies for breast surgery and reduce opioid needs.

Why it matters

Who can join: the full rules

Inclusion Criteria:

1. Breast cancer female patients.
2. ASA class II and III.
3. Age ≥ 18 and ≤ 65 Years.
4. Body mass index (BMI): \> 20 kg/m2 and \< 35 kg/m2.
5. Type of surgery; elective breast cancer surgery modified radical mastectomy combined with axillary dissection.

Exclusion Criteria:

1. Patient refusal.
2. Age \<18 years or \>65 years.
3. BMI \<20 kg/m2 and \>35 kg/m2.
4. Major medical conditions.
5. Pregnancy or lactation.

Where it's running

• National Cancer Institute - Cairo University
  Cairo, Egypt Recruiting

Study contacts

• Study coordinator: Ayman Sharawy Abdelrahman Aboul Nasr, MD
• Email: ayman.sharawy@nci.cu.edu.eg
• Phone: 01282649008

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.