Bilateral maxillary nerve block timing to reduce intraoperative remifentanil use in septorhinoplasty
Official title: Effect of Bilateral Maxillary Block on Intraoperative Remifentanil Consumption in Septorhinoplasty Surgery
Run by Atatürk Chest Diseases and Chest Surgery Training and Research Hospital · NCT07608861 · Data updated 2026-11-12
This trial tests whether giving a bilateral maxillary nerve block before or after intubation affects how much remifentanil is used during septorhinoplasty in adults.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years to 65 Years |
| Sex | All |
| Enrollment | 80 (estimated) |
| Sponsor | Atatürk Chest Diseases and Chest Surgery Training and Research Hospital Academic / other |
| Locations | 1 site (Yenimahalle, Ankara) |
| Status | Recruiting |
| Started | June 1, 2026 |
| Main results expected | December 1, 2026 |
| Study ends | December 20, 2026 |
| Registry record updated | June 2, 2026 |
| Trial ID | NCT07608861 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Adults aged 18–65 with ASA I–II undergoing septorhinoplasty, without prior nasal surgery or chronic opioid use, and without allergies to local anesthetics.
✕Probably not a fit
Patients with prior nasal surgery, chronic opioid use, or contraindications to local anesthetics may not benefit.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This interventional study compares two timing strategies for bilateral maxillary nerve block in adults undergoing septorhinoplasty. The aim is to see if the block timing (pre-extubation vs post-intubation) changes intraoperative remifentanil consumption and postoperative analgesia. Eligible participants are 18–65 years old with ASA I–II undergoing septorhinoplasty, excluding those with prior nasal surgery, chronic opioid use, or known allergies to local anesthetics. The procedure is conducted at Ankara Etlik City Hospital with a lead sponsor at Atatürk Chest Diseases and Chest Surgery Training and Research Hospital. Outcomes focus on intraoperative opioid use and early post-operative pain control.
Why it matters
Potential benefit: If successful, timing the maxillary block could reduce perioperative opioid needs and improve pain management for patients undergoing septorhinoplasty.
How similar studies have gone: Previous regional anesthesia approaches have shown reduced intraoperative opioid requirements in facial surgeries, but this specific timing comparison is relatively novel.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * 18 to 65 years old * American Society of Anesthesiologists (ASA) physical status I-II * Body mass index 18 to 30 kg/m2 * Septorhinoplasty surgery Exclusion Criteria: * Patient refusing the procedure * Patients who have previously undergone nasal surgery * Chronic opioid or analgesic use * Patients with allergies to local anesthetics * Patients with Hypertension * Patients receiving antihypertensive treatment.
Where it's running
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Ankara Etlik City Hospital
Yenimahalle, Ankara, Turkey (Türkiye) Recruiting
Study contacts
- Study coordinator: Musa Zengin, Associate Professor
- Email: musazengin@gmail.com
- Phone: 05307716235
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
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Using heart rate variability and anxiety to predict emergence agitation after septorhinoplasty
This study will see if preoperative heart rate variability and anxiety levels can predict emergence agitation in adults having elective septorhinoplasty under general anesthesia.
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AI-assisted analgesia copilot to guide remifentanil dosing during general anesthesia
This project will test an AI 'co-pilot' that monitors multiple physiological signals during general anesthesia to guide remifentanil dosing and reduce over- or under-dosing for adults having elective surgeries of 2–4 hours.
-
Dexmedetomidine infusion to reduce intraoperative remifentanil use during laparoscopic abdominal surgery
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.