BDNF Levels in Spine Pain Patients and Disc Degeneration

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

Researchers will measure serum BDNF and analyze its correlation with Pfirrmann grade of disc degeneration and IL-1β levels in patients with chronic low back pain due to herniation or stenosis. Blood samples will be collected and analyzed using ELISA to quantify BDNF and inflammatory markers. The study is observational and does not assign any treatment, focusing on understanding biological associations in the affected population. Enrollment is limited to adults with relevant imaging findings and excludes other spine or systemic inflammatory conditions.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* lumbar disc herniation
* lumbar spinal canal stenosis
* patients who have MRI

Exclusion Criteria:

* spine fracture
* spine infection
* spine tumor
* rhematoid arthritis
* ankylosing spondylitis
* systemic lupus erythematosus
* peripheral neuropathy
* fibromyalgia
* patient taking antidepressant, antipsychotics, acetylcholiesterase inhibitor

Where it's running

• Ji Hee
  Daegu, Daegu, South Korea Recruiting

Study contacts

• Study coordinator: JIHEE Hong
• Email: swon13@daum.net
• Phone: 01046794343

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.