Austrian PBC Registry
Official title: Characterisation of Patients With Primary Biliary Cholangitis in Austria - A Prospective Registry and Biobank
Run by Medical University of Vienna · NCT07598669 · Data updated 2026-11-12
This registry follows adults with primary biliary cholangitis in Austrian centers to see how the disease develops over time and how biomarkers relate to complications and symptoms.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 500 (estimated) |
| Sponsor | Medical University of Vienna Academic / other |
| Locations | 11 sites (Klagenfurt, Carinthia and 10 other locations) |
| Status | Recruiting |
| Started | March 18, 2026 |
| Main results expected | December 2040 |
| Study ends | December 2040 |
| Registry record updated | May 20, 2026 |
| Trial ID | NCT07598669 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Adults with a confirmed diagnosis of primary biliary cholangitis who are treated at participating Austrian centers and provide informed consent.
✕Probably not a fit
Patients who do not wish to participate or who withdraw consent will not be exposed to any additional procedures beyond routine care.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This is a prospective, multicenter registry of patients with primary biliary cholangitis in Austria. Data from medical records and laboratory tests will be collected, with regular follow-up visits typically every 3–6 months. Optional biobank participation may store serum, plasma, and liver tissue for future research. No study-specific interventions are required; care will follow standard clinical practice at each center. The study will also examine overlapping liver diseases and the severity of liver damage to better understand disease progression and complications.
Why it matters
Potential benefit: Participants may contribute to a better understanding of PBC over time, which could help improve future patient care and research.
How similar studies have gone: Observational registries in hepatology have provided valuable insights into disease progression and outcomes, supporting the potential usefulness of this approach.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Age \>18 years * Confirmed diagnosis of primary biliary cholangitis (at least two of the following three criteria must be fulfilled: persistent elevation of alkaline phosphatase above the upper limit of normal for at least 6 months; presence of antimitochondrial antibodies or PBC-specific antinuclear antibodies; characteristic histopathology) * Written informed consent for participation in the registry Exclusion Criteria: * Withdrawal of written informed consent
Where it's running
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Medizinische Universität Wien
Vienna, State of Vienna, Austria Recruiting -
Klinikum Klagenfurt am Wörthersee
Klagenfurt, Carinthia, Austria Not yet recruiting -
Universitätsklinikum St. Pölten
Sankt Pölten, Lower Austria, Austria Not yet recruiting -
Universitätsklinikum Salzburg
Salzburg, State of Salzburg, Austria Not yet recruiting -
Klinik Landstraße
Vienna, State of Vienna, Austria Not yet recruiting -
Klinik Ottakring
Vienna, State of Vienna, Austria Not yet recruiting
Show 5 more locations
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Medizinische Universität Graz
Graz, Styria, Austria Not yet recruiting -
Medizinische Universität Innsbruck
Innsbruck, Tyrol, Austria Not yet recruiting -
Ordensklinikum Linz - Barmherzige Schwestern
Linz, Upper Austria, Austria Not yet recruiting -
Kepler Universitätsklinikum
Linz, Upper Austria, Austria Not yet recruiting -
Klinikum Wels-Grieskirchen
Wels, Upper Austria, Austria Not yet recruiting
Study contacts
- Study coordinator: Michael Trauner, MD
- Email: Michael.Trauner@meduniwien.ac.at
- Phone: +43 1 40400 47410
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.