Audit of surgery and chemotherapy for abdominal cancers
Official title: A Prospective Audit of Perioperative Parameters of Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy (CRS-HIPEC)
Run by Tata Memorial Centre · NCT02754115 · Data updated 2026-11-12
This study tests whether a combination of surgery and heated chemotherapy can help people with advanced colorectal and ovarian cancers live longer and feel better.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years to 70 Years |
| Sex | All |
| Enrollment | 400 (estimated) |
| Sponsor | Tata Memorial Centre Academic / other |
| Drugs / interventions | chemotherapy |
| Locations | 1 site (Mumbai, Maharashtra) |
| Status | Recruiting |
| Started | April 2016 |
| Main results expected | December 2026 |
| Study ends | January 2027 |
| Registry record updated | November 21, 2024 |
| Trial ID | NCT02754115 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are adults aged 18 to 70 with colorectal or gynecological cancers who are eligible for CRS with HIPEC.
✕Probably not a fit
Patients outside the age range of 18 to 70 or those classified as ASA Class IV and above may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational study evaluates the outcomes of cytoreductive surgery (CRS) combined with hyperthermic intraperitoneal chemotherapy (HIPEC) in patients with peritoneal carcinomatosis from colorectal and ovarian cancers. The study focuses on the effectiveness of this treatment approach in improving patient survival and quality of life. It involves the removal of visible metastatic disease followed by chemotherapy administered at elevated temperatures to target remaining microscopic cancer cells. The study aims to gather data on the procedure's safety and efficacy in a selected patient population.
Why it matters
Potential benefit: If successful, this approach could significantly enhance survival rates and quality of life for patients with advanced abdominal cancers.
How similar studies have gone: Previous studies have shown promising results with CRS and HIPEC, indicating potential for significant patient benefit.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: 1. Age between 18 to 70 years 2. ASA Class I to III 3. Colorectal and gynecological oncology cases posted for CRS with HIPC. Exclusion Criteria: 1. Age less than 18 and more than 70 years 2. ASA Class IV and above
Where it's running
-
Tata Memorial Hospital
Mumbai, Maharashtra, India Recruiting
Study contacts
- Principal investigator: Sohan L solanki — Tata Memorial Centre
- Study coordinator: Sohan L Solanki, MD
- Email: me_sohans@yahoo.co.in
- Phone: +919869253201
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.