Audit of surgery and chemotherapy for abdominal cancers
A Prospective Audit of Perioperative Parameters of Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy (CRS-HIPEC)
This study tests whether a combination of surgery and heated chemotherapy can help people with advanced colorectal and ovarian cancers live longer and feel better.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 400 (estimated) |
| Ages | 18 Years to 70 Years |
| Sex | All |
| Sponsor | Tata Memorial Centre Academic / other |
| Drugs / interventions | chemotherapy |
| Locations | 1 site (Mumbai, Maharashtra) |
| Trial ID | NCT02754115 on ClinicalTrials.gov |
What this trial studies
This observational study evaluates the outcomes of cytoreductive surgery (CRS) combined with hyperthermic intraperitoneal chemotherapy (HIPEC) in patients with peritoneal carcinomatosis from colorectal and ovarian cancers. The study focuses on the effectiveness of this treatment approach in improving patient survival and quality of life. It involves the removal of visible metastatic disease followed by chemotherapy administered at elevated temperatures to target remaining microscopic cancer cells. The study aims to gather data on the procedure's safety and efficacy in a selected patient population.
Who should consider this trial
Good fit: Ideal candidates are adults aged 18 to 70 with colorectal or gynecological cancers who are eligible for CRS with HIPEC.
Not a fit: Patients outside the age range of 18 to 70 or those classified as ASA Class IV and above may not benefit from this study.
Why it matters
Potential benefit: If successful, this approach could significantly enhance survival rates and quality of life for patients with advanced abdominal cancers.
How similar studies have performed: Previous studies have shown promising results with CRS and HIPEC, indicating potential for significant patient benefit.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: 1. Age between 18 to 70 years 2. ASA Class I to III 3. Colorectal and gynecological oncology cases posted for CRS with HIPC. Exclusion Criteria: 1. Age less than 18 and more than 70 years 2. ASA Class IV and above
Where this trial is running
Mumbai, Maharashtra
- Tata Memorial Hospital — Mumbai, Maharashtra, India (Recruiting)
Study contacts
- Principal investigator: Sohan L solanki — Tata Memorial Centre
- Study coordinator: Sohan L Solanki, MD
- Email: me_sohans@yahoo.co.in
- Phone: +919869253201
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.