Clinical trial No longer in our active list Interventional Ages 18 and up

Audio-based intervention for reducing depression symptoms

Official title: Audio-based Mental Health Intervention Study

Run by Penn State University · NCT05555745 · Data updated 2026-05-14

This study is no longer in our active list. It may have stopped recruiting or finished. The details below are as of 2026-05-14 and are kept for reference. Check ClinicalTrials.gov for its current status, or see similar studies below.

This study tests whether an audio program can help adults with moderate or higher depression feel better compared to a self-monitoring approach.

Quick facts

Study typeInterventional
Ages18 Years and up
SexAll
Enrollment126 (estimated)
SponsorPenn State University
Academic / other
Locations1 site (University Park, Pennsylvania)
Trial IDNCT05555745 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates are adults aged 18 or older who exhibit moderate to severe depressive symptoms.

Probably not a fit

Patients with mild depression or those unable to engage with English-language audio content may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study evaluates an audio-based digital intervention aimed at alleviating depressive symptoms in adults. Participants with moderate or higher depression will be randomly assigned to either a behavioral activation intervention or a self-monitoring control intervention. The effectiveness of these interventions will be assessed at multiple time points, including baseline, mid-intervention, post-intervention, and follow-up. The study seeks to understand how these audio-based approaches can impact mental health outcomes.

Why it matters

Potential benefit: If successful, this intervention could provide an accessible and effective tool for individuals struggling with depression.

How similar studies have gone: Other studies have shown promise with audio-based interventions for mental health, suggesting potential for success in this approach.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Adult age 18 or older
* Score in the moderate or higher range on the BDI-FastScreen
* Moderate or higher depression confirmed by DIAMOND interview
* Proficient English reading, writing, and speaking ability
* Able to provide consent
* Provide informed consent

Exclusion Criteria:

* Below 18 years of age
* Score below the moderate range on the BDI-FastScreen
* DIAMOND interview does not confirm moderate or higher depression
* Unable to read, write, and speak in English
* Unable to provide consent
* Do not provide informed consent

Where it's running

  • The Pennsylvania State University
    University Park, Pennsylvania, United States
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.