Audio-based intervention for reducing depression symptoms

Audio-based Mental Health Intervention Study

Not applicable Interventional Penn State University · NCT05555745

This study tests whether an audio program can help adults with moderate or higher depression feel better compared to a self-monitoring approach.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment126 (estimated)
Ages18 Years and up
SexAll
SponsorPenn State University Academic / other
Locations1 site (University Park, Pennsylvania)
Trial IDNCT05555745 on ClinicalTrials.gov

What this trial studies

This study evaluates an audio-based digital intervention aimed at alleviating depressive symptoms in adults. Participants with moderate or higher depression will be randomly assigned to either a behavioral activation intervention or a self-monitoring control intervention. The effectiveness of these interventions will be assessed at multiple time points, including baseline, mid-intervention, post-intervention, and follow-up. The study seeks to understand how these audio-based approaches can impact mental health outcomes.

Who should consider this trial

Good fit: Ideal candidates are adults aged 18 or older who exhibit moderate to severe depressive symptoms.

Not a fit: Patients with mild depression or those unable to engage with English-language audio content may not benefit from this study.

Why it matters

Potential benefit: If successful, this intervention could provide an accessible and effective tool for individuals struggling with depression.

How similar studies have performed: Other studies have shown promise with audio-based interventions for mental health, suggesting potential for success in this approach.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Adult age 18 or older
* Score in the moderate or higher range on the BDI-FastScreen
* Moderate or higher depression confirmed by DIAMOND interview
* Proficient English reading, writing, and speaking ability
* Able to provide consent
* Provide informed consent

Exclusion Criteria:

* Below 18 years of age
* Score below the moderate range on the BDI-FastScreen
* DIAMOND interview does not confirm moderate or higher depression
* Unable to read, write, and speak in English
* Unable to provide consent
* Do not provide informed consent

Where this trial is running

University Park, Pennsylvania

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Depressive Symptomsdigital interventionsmhealthdepressionbehavioral activationpodcastsself-help
Last reviewed 2026-06-09 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.