Audio-based intervention for reducing depression symptoms
Official title: Audio-based Mental Health Intervention Study
Run by Penn State University · NCT05555745 · Data updated 2026-05-14
This study is no longer in our active list. It may have stopped recruiting or finished. The details below are as of 2026-05-14 and are kept for reference. Check ClinicalTrials.gov for its current status, or see similar studies below.
This study tests whether an audio program can help adults with moderate or higher depression feel better compared to a self-monitoring approach.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 126 (estimated) |
| Sponsor | Penn State University Academic / other |
| Locations | 1 site (University Park, Pennsylvania) |
| Trial ID | NCT05555745 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are adults aged 18 or older who exhibit moderate to severe depressive symptoms.
✕Probably not a fit
Patients with mild depression or those unable to engage with English-language audio content may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This study evaluates an audio-based digital intervention aimed at alleviating depressive symptoms in adults. Participants with moderate or higher depression will be randomly assigned to either a behavioral activation intervention or a self-monitoring control intervention. The effectiveness of these interventions will be assessed at multiple time points, including baseline, mid-intervention, post-intervention, and follow-up. The study seeks to understand how these audio-based approaches can impact mental health outcomes.
Why it matters
Potential benefit: If successful, this intervention could provide an accessible and effective tool for individuals struggling with depression.
How similar studies have gone: Other studies have shown promise with audio-based interventions for mental health, suggesting potential for success in this approach.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Adult age 18 or older * Score in the moderate or higher range on the BDI-FastScreen * Moderate or higher depression confirmed by DIAMOND interview * Proficient English reading, writing, and speaking ability * Able to provide consent * Provide informed consent Exclusion Criteria: * Below 18 years of age * Score below the moderate range on the BDI-FastScreen * DIAMOND interview does not confirm moderate or higher depression * Unable to read, write, and speak in English * Unable to provide consent * Do not provide informed consent
Where it's running
-
The Pennsylvania State University
University Park, Pennsylvania, United States Recruiting
Study contacts
- Study coordinator: Gavin Rackoff, M.S.
- Email: gnr18@psu.edu
- Phone: 814-863-0115
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
-
Morning Activation to Boost Mood After Stroke
A six-week behavioral program is tested to see if it helps mood and daily functioning in adults who had a stroke and feel depressed or slow to get going in the morning.
-
Sleep More, Stress Less with Neuralli Mood
This 90-day, open-label study tests whether daily Neuralli Mood capsules can help adults feel less stressed, sleep better, and improve mood and burnout symptoms.
-
Blended Baduanjin and Green Tea Program for Depressive Symptoms in Older Adults
This study tests whether a 12-week combo of gentle Baduanjin exercise and green tea consumption can help reduce depressive symptoms and improve gut health and quality of life in Hong Kong’s community-dwelling adults aged 65–84.
-
Metformin added to antidepressants for depression with obesity in Pakistani adults
This study tests whether adding metformin to antidepressant therapy helps reduce depressive symptoms and BMI in adults with depression and overweight/obesity in Pakistan.
-
rTMS with aerobic exercise for older adults with mild cognitive impairment and depressive symptoms
This trial tests whether rTMS alone or rTMS plus stationary cycling can improve thinking skills and mood in older adults with MCI and depression.
-
Subanesthetic Ketamine for Depressive Symptoms in ICU Patients
This study tests whether a short course of low-dose ketamine can help reduce depressive symptoms in adults who are in the ICU.
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.