Assessing major complications in patients with thoracic aortic aneurysm

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to evaluate the incidence of major complications in patients diagnosed with small to moderate thoracic aortic aneurysms over a five-year follow-up period. It will investigate various systemic factors, such as high blood pressure and sleep disorders, that may influence the progression of the aneurysm. Participants will undergo regular imaging and clinical assessments to monitor their condition and identify any complications that arise. The study seeks to fill the gap in existing data regarding the risks associated with thoracic aortic aneurysms.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Documentation of an aortic root aneurysm \> 40 mm
* Agreement to participate to a longitudinal study and available for a 5 years follow-up

Exclusion Criteria:

* Presence of comorbidities or pathology with a prognosis of less than 1 year
* Personal or family history of genetically documented elastic tissue disease or patient meeting the GAND clinical criteria suggestive of Marfan disease
* High-grade mitra-aortic valve disease, even if asymptomatic
* Unbalanced hypertension ≥ 180/110 mmHg
* Aneurysm (regardless of thoracic or abdominal location) ≥ 50 mm
* Aneurysm (regardless of thoracic or abdominal location) with documented progression of more than 5 mm over one year
* History of aortic surgery or endovascular intervention and history of type B aortic dissection of medical treatment
* Renal insufficiency on dialysis, or GFR\< 30 ml/mn (CKD-EPI)

Where it's running

• CHU Lille
  Lille, Please Choose..., France Recruiting

Study contacts

• Principal investigator: Pascal DELSART, MD — University Hospital, Lille
• Study coordinator: Pascal DELSART, MD
• Email: pascal.DELSART@chru-Lille.fr
• Phone: 0320445962

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

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• Using presepsin levels to guide antibiotic treatment in thoracic aorta surgery patients

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.