Assessing long-term kidney outcomes in ICU patients with acute kidney injury
Impact of the Characteristics of Acute Renal Failure in Intensive Care on the Long-term Renal Prognosis: Prospective Multicenter Cohort Study
This study looks at how different types of kidney injury in ICU patients affect their kidney health in the long run.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 860 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | University Hospital, Clermont-Ferrand Academic / other |
| Locations | 2 sites (Clermont-Ferrand and 1 other locations) |
| Trial ID | NCT05247502 on ClinicalTrials.gov |
What this trial studies
This multicenter observational study aims to evaluate how different characteristics of Acute Kidney Injury (AKI) affect long-term renal prognosis in patients admitted to Intensive Care Units (ICUs). Patients hospitalized for more than 24 hours will be classified into three groups based on their AKI status: no AKI, transient AKI, and persistent AKI. Data regarding renal function during their ICU stay, as well as baseline kidney function, will be collected to analyze the impact of AKI on long-term outcomes. The study will take place across four ICUs in Clermont-Ferrand, France.
Who should consider this trial
Good fit: Ideal candidates for this study are ICU patients who have been hospitalized for more than 24 hours.
Not a fit: Patients under 18 years old, pregnant individuals, and those with chronic kidney conditions prior to ICU admission may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could provide insights that improve long-term kidney health outcomes for ICU patients who experience acute kidney injury.
How similar studies have performed: Other studies have explored the effects of acute kidney injury on long-term outcomes, suggesting that this approach has potential for meaningful insights.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patients who are hospitalized for more than 24 hours in ICU will be eligible to participate in the study. Exclusion Criteria: * patients who are younger than 18 years, * those who are pregnant, * those who have chronic extrarenal epuration before their admission to the ICU, * those who are admitted for kidney transplantation, * those under the safeguard of justice, and those who refuse to participate in the study.
Where this trial is running
Clermont-Ferrand and 1 other locations
- Centre Jean-Perrin — Clermont-Ferrand, France (Recruiting)
- CHU clermont-ferrand — Clermont-Ferrand, France (Recruiting)
Study contacts
- Principal investigator: Alexandre Lautrette — University Hospital, Clermont-Ferrand
- Study coordinator: Lise Laclautre
- Email: promo_interne_drci@chu-clermontferrand.fr
- Phone: 334.73.754.963
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.