Assessing Lithium Levels and Suicidal Behavior in Depressed Patients

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to evaluate the basal plasma lithium levels in patients with major depressive disorder, both unipolar and bipolar, and their association with suicidal events. It will compare lithium levels between patients who have experienced suicidal events in the past year and those who have not. Participants will undergo a clinical assessment and provide a blood sample for lithium measurement. The study seeks to understand the relationship between lithium levels and factors such as suicidal ideation, impulsiveness, and emotional lability.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* 18 years old or over
* Current major depressive episode according to the DSM-5 (Diagnostic and Statistical Manual of Mental Disorders) criteria
* No lithium-based treatment over the last 12 months
* For suicide attempters/ideations only : suicidal event over the last 12 months
* For affective controls only : no suicidal event over the last 12 months

Exclusion Criteria:

* Lifetime diagnosis of schizoaffective disorder, schizophrenia or psychosis
* Pregnancy or breastfeeding
* Deprivation of freedom (by judicial or administrative decision)
* Legal protection measure (guardianship or curators)
* Inability to understand experimental procedures
* No affiliation to the French National Social Security System
* No consent to participate in the study

Where it's running

• CHU Montpellier
  Montpellier, France Recruiting

Study contacts

• Study coordinator: Bénédicte NOBILE, Pharma D, PhD
• Email: b-nobile@chu-montpellier.fr
• Phone: +33467338581

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.