Assessing knee osteoarthritis in patients with tibial plateau fractures in Norrbotten
Knee Osteoarthritis in the Region of Norrbotten (KORN)
This study looks at how common knee osteoarthritis is in people from Norrbotten, Sweden who had tibial plateau fractures, and it also checks how different factors might affect their recovery.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 500 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | Umeå University Academic / other |
| Locations | 1 site (Luleå, Norrbotten County) |
| Trial ID | NCT06451510 on ClinicalTrials.gov |
What this trial studies
This observational study aims to evaluate the prevalence of radiographic knee osteoarthritis in patients from the Norrbotten region of Sweden who experienced tibial plateau fractures between 2001 and 2015. It involves clinical examinations and radiographic assessments, alongside condition-specific and general health-related quality of life evaluations using established scoring tools. The study also investigates potential risk factors such as age, gender, BMI, and fracture treatment methods that may influence long-term functional outcomes.
Who should consider this trial
Good fit: Ideal candidates are patients from the Norrbotten region who underwent tibial plateau fractures between 2001 and 2015.
Not a fit: Patients with pre-existing osteoarthritis, cognitive disorders, or those who have had severe injuries to the knee may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could provide insights into the long-term effects of tibial plateau fractures on knee osteoarthritis, potentially guiding better management strategies for affected patients.
How similar studies have performed: While this study builds on existing knowledge of knee osteoarthritis, the specific focus on tibial plateau fractures and their long-term outcomes is relatively novel.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patients from the region of Norrbotten (northern part of Sweden) who underwent tibial plateau fracture between the years of 2001 and 2015 Exclusion Criteria: * Death without bilateral weighted X-ray minimum 5 years post injury * Open growth plate in distal femur and/or proximal tibia * Extraarticular or isolated eminentia fracture * OA prior to injury * Having a rheumatic disorder involving joints * Earlier and/or later severe injury to the index knee * Having cognitive disorders disqualifying from the study
Where this trial is running
Luleå, Norrbotten County
- Sunderby Central Hospital of Norrbotten — Luleå, Norrbotten County, Sweden (Recruiting)
Study contacts
- Study coordinator: Przemyslaw T Paradowski, MD, PhD
- Email: przemyslaw.paradowski@umu.se
- Phone: -46 708329574
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.