Using PRP treatment after ACL reconstruction to improve recovery

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study investigates the efficiency and safety of platelet-rich plasma (PRP) treatment following anterior cruciate ligament (ACL) reconstruction. ACL injuries are common and often lead to long-term complications such as osteoarthritis. The trial aims to assess whether PRP can enhance healing and reduce the risk of arthritis after surgery. Participants will be monitored for their recovery and any adverse effects associated with the treatment.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* subject is 18-45 years old
* subject has BMI \< 40 kg/m2
* subject had ACL reconstrution
* small asymptomatic meniscal lesions that won't require repair
* subject must be willing to abstain from other intra-articular treatments of the knee for the duration of the study.
* subject is willing to discontinue all analgesics including nonsteroidal anti-inflammatory drugs (NSAIDs), except tramadol and paracetamol, at least one month before the synovial fluid aspiration and through the completion of the study
* subject is able to understand and comply with the requirements of the study and voluntarily provides consent

Exclusion Criteria:

* subject has a history of metabolic diseases, endocrine disorders, rheumatic and connective tissue diseases, cancer, hormonal contraception, steroid therapy, antibiotic therapy
* subject had an intraarticular injection into the affected joint
* subject had previous operations (beside ACL reconstruction) or fractures of the affected limb
* subject has a history of nicotine, alcohol, or drug addiction
* subject has a meniscal tear that requires suturing or total meniscectomy seen on MRI
* subject has multi-ligament knee injuries or multi-organ injury
* subject has significant varus or valgus deformity greater than 10 degrees in either knee, determined by an X-ray

Where it's running

• Dawid Szwedowski
  Torun, Poland Recruiting

Study contacts

• Study coordinator: Dawid Szwedowski, MD, PhD
• Email: dszwedow@yahoo.com
• Phone: 608075237

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.