Assessing kidney function and blood breakdown after a heart procedure for atrial fibrillation

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This project aims to evaluate the effects of pulsed-field ablation on hemolysis and renal function in patients with atrial fibrillation. It will involve measuring red blood cell microparticles and hemoglobinuria immediately after the procedure and one to three days post-procedure. The study will include patients with paroxysmal and persistent atrial fibrillation who are eligible for catheter ablation, while excluding those with hematologic disorders or on dialysis. A total of 100 patients will be enrolled to assess the relationship between the number of ablation applications and the degree of hemolysis on renal function.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* symptomatic paroxysmal or non-paroxysmal atrial fibrillation

Exclusion Criteria:

* known hematologic disorders
* disorders associated with increased hemolysis
* known significant hepatic disease
* patient in permanent hemodialysis

Where it's running

• Cardiocenter, 3rd Medical School, Charles University and University Hospital Kralovske Vinohrady
  Prague, Czech Republic Recruiting

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.