Assessing how common orthostatic tremor is in patients with unsteadiness

Prevalence of Orthostatic Tremor by Surface Electromyographic Recording in Patients Reporting Unsteadiness

Observational Assistance Publique - Hôpitaux de Paris · NCT04844203

This study is trying to find out how common orthostatic tremor is in patients who feel unsteady and have been referred for nerve testing due to peripheral neuropathy.

Quick facts

Study typeObservational
Enrollment100 (estimated)
Ages18 Years and up
SexAll
SponsorAssistance Publique - Hôpitaux de Paris Academic / other
Locations1 site (Paris)
Trial IDNCT04844203 on ClinicalTrials.gov

What this trial studies

This observational study aims to systematically assess the prevalence of orthostatic tremor (OT) in patients experiencing postural instability who are referred for electroneuromyography (ENMG) due to peripheral neuropathy. The study will analyze demographic, clinical, and electrophysiological characteristics of these patients, confirming the presence of OT through surface EMG. By evaluating the correlation between OT and various neuropathy scores, the study seeks to provide a clearer understanding of the relationship between these conditions.

Who should consider this trial

Good fit: Ideal candidates include adults aged 18 and older who experience instability when standing and are referred for an ENMG.

Not a fit: Patients who are unable to stand, under legal protection, or those who refuse to participate will not benefit from this study.

Why it matters

Potential benefit: If successful, this study could enhance the diagnosis and management of patients with orthostatic tremor and related neuropathies.

How similar studies have performed: While the prevalence of orthostatic tremor has been studied, this specific approach focusing on patients with peripheral neuropathy is novel and has not been extensively tested.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Age ≥ 18 years old
* All patients complaining of instability when standing up and referred for an ENMG
* Patient informed and having expressed his non-opposition to participating in the research

Exclusion Criteria:

* Patient's refusal to participate in the study
* Impossibility to stand
* No affiliation to health insurance
* Patients under a legal protection measure or unable to express their will
* Patient under the State Medical Assistance (AME)
* Patient under 18 years old
* Pregnant women, parturients and breast-feeding mothers

Where this trial is running

Paris

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Orthostatic TremorNeuropathyElectroneuromyographyPolygraphyUnsteadinessTremorAnti-MAG neuropathyChronic demyelinating inflammatory neuropathy
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.