Assessing harm reduction services for drug users

Culturally Response Integrated Harm Reduction Services for Black and Latinx People Who Use Drugs

Not applicable Interventional NYU Langone Health · NCT05776316

This study is testing a new approach to help Black and Latinx individuals who use drugs get better support and services compared to the usual options.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment200 (estimated)
Ages18 Years and up
SexAll
SponsorNYU Langone Health Academic / other
Locations3 sites (New Haven, Connecticut and 2 other locations)
Trial IDNCT05776316 on ClinicalTrials.gov

What this trial studies

This study evaluates the effectiveness of an integrated harm reduction intervention (IHRI) compared to standard harm reduction services in improving service utilization among Black and Latinx individuals who use drugs. Participants must be at least 18 years old and have misused opioids or other substances in the past 30 days. The study aims to provide insights into how tailored interventions can better serve marginalized communities affected by substance abuse. The research will be conducted across multiple locations, including NYU Langone Health and Yale University.

Who should consider this trial

Good fit: Ideal candidates are Black and Latinx individuals aged 18 and older who have misused opioids or other substances in the past month.

Not a fit: Patients with severe mental health issues, such as active suicidal ideation or unstable psychotic disorders, may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could enhance access to and effectiveness of harm reduction services for marginalized populations struggling with substance use.

How similar studies have performed: Other studies have shown promise in utilizing harm reduction approaches, but this integrated intervention is a novel application targeting specific racial and ethnic groups.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* at least 18 years of age
* self-identified as misusing opioids +/- other substances (stimulants) in the past 30 days, confirmed by interview using DSM-5 criteria
* English or Spanish speaking
* able to provide informed consent.

Exclusion Criteria:

* inability to provide informed consent or participate in the study procedures as proposed in the consent
* active suicidal or homicidal ideation or an unstable psychotic disorder (schizophrenia, schizoaffective disorder) or mood disorder (bipolar disorder, severe major depressive disorder)
* an unwillingness to be randomized.
* are prisoners

Where this trial is running

New Haven, Connecticut and 2 other locations

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Drug UseSubstance AbuseMental IllnessHarm ReductionLatinx/HispanixBlack/African AmericanCocaineOpioids
Last reviewed 2026-06-09 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.