Assessing Geriatric Health in Older Cancer Patients
Predictive Value of Geriatric Oncology Screening and Geriatric Assessment in Older Patients With Solid Cancers (PROGNOSIS-RCT)
This study is testing whether a special health check for older cancer patients can help them feel better and improve their treatment outcomes compared to standard care.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 322 (estimated) |
| Ages | 70 Years and up |
| Sex | All |
| Sponsor | Odense University Hospital Academic / other |
| Locations | 1 site (Odense, Southern Denmark) |
| Trial ID | NCT04686851 on ClinicalTrials.gov |
What this trial studies
This clinical trial examines the impact of Comprehensive Geriatric Assessment on older patients with solid cancers who are considered frail. Participants aged 70 and above, screened for frailty using the Geriatric 8 tool, will be randomly assigned to receive either the geriatric assessment and intervention or standard oncologic treatment. The study aims to evaluate how this additional assessment influences patient outcomes and prognosis over a 12-month period. A multidisciplinary team will conduct the assessments and follow-ups to ensure comprehensive care.
Who should consider this trial
Good fit: Ideal candidates are cancer patients aged 70 or older, living in Southern Denmark, and identified as frail.
Not a fit: Patients who are unable to speak or understand Danish or those already receiving treatment for other cancers may not benefit from this study.
Why it matters
Potential benefit: If successful, this approach could improve treatment outcomes and quality of life for older cancer patients by addressing their unique health needs.
How similar studies have performed: Other studies have shown promising results with similar geriatric assessment approaches, indicating potential for success in this trial.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Age ≥ 70 years * Living in the region of Southern Denmark * Newly diagnosed solid tumours assessed eligible for antineoplastic treatment * Vulnerable or frail (G8 ≤ 14) Exclusion Criteria: * Inability to speak or understand Danish * Inability to give informed consent * Already consulting geriatric outpatient clinic * Already receiving active treatment for other coexisting solid tumours, haematologic cancers, or non-melanoma skin cancer or has received oncologic treatment the past year
Where this trial is running
Odense, Southern Denmark
- Odense University Hospital — Odense, Southern Denmark, Denmark (Recruiting)
Study contacts
- Principal investigator: Ann-Kristine W Giger, MD — Department of Geriatric Medicine, Odense University Hospital, Odense
- Study coordinator: Jesper Ryg, MD
- Email: Jesper.Ryg@rsyd.dk
- Phone: 60152610
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.