Assessing fracture risk in post-menopausal women using BBCT-hip

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This clinical study evaluates the accuracy of the BBCT-hip methodology, which predicts the risk of hip fractures based on individual height, weight, and CT scans of the femur. It involves enrolling 150 subjects who have experienced a fracture and 150 control subjects without fractures. Both groups will undergo CT scans, and the predictive accuracy of BBCT-hip will be assessed through a transversal study and a longitudinal follow-up of the control group. The goal is to determine how well BBCT-hip can differentiate between those at risk of fractures and those who are not.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* caucasic post-menopausal women resident in Emilia-Romagna
* menopause (\>= 45 years)

Exclusion Criteria:

* tumours
* not free living
* Chronic diseases with severe organ failure / endocrine diseases of parathyroid, thyroid, adrenal gland / intestinal malabsorption, osteomalacia / Paget bone / rheumatoid arthritis. Neurodegenerative diseases
* Long-term continuous therapy (\>3 months) with corticosteroids and proton pump inhibitors or aromatase inhibitors
* Previous femur fractures
* Presence of hip/knee prosthesis

only for the fracturegroup:

* presence of fixation devices after the fracture
* femur fracture due to high energy trauma

Where it's running

• Rizzoli Orthopaedic Institute
  Bologna, Italy Recruiting
• Rizzoli Orthopaedic Institute
  Bologna, Italy Recruiting

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.