Assessing Aquablation Therapy Outcomes for Prostate Cancer Patients

PRCT001 Aquablation theraPy Outcomes in pRostate Cancer patienTs

NA · PROCEPT BioRobotics · NCT06051942

This study is testing a new robotic water treatment to see if it can safely remove prostate tissue and improve urinary symptoms in men with localized prostate cancer.

Quick facts

PhaseNA
Study typeInterventional
Enrollment125 (estimated)
AgesN/A to 80 Years
SexMale
SponsorPROCEPT BioRobotics (industry)
Locations6 sites (La Mesa, California and 5 other locations)
Trial IDNCT06051942 on ClinicalTrials.gov

What this trial studies

This clinical trial evaluates the safety and effectiveness of the AQUABEAM Robotic System in removing prostate tissue in patients with localized prostate cancer and lower urinary tract symptoms. Participants will undergo assessments at baseline and follow-ups for up to 12 months to monitor outcomes. The intervention involves a robotic waterjet treatment designed to improve urinary symptoms while addressing cancerous tissue.

Who should consider this trial

Good fit: Ideal candidates include men with localized prostate cancer (Gleason Grade Group 1-3) and significant urinary symptoms.

Not a fit: Patients with advanced cancer stages or those who have undergone previous surgical treatments for benign prostatic hyperplasia may not benefit from this study.

Why it matters

Potential benefit: If successful, this treatment could provide a minimally invasive option for patients with localized prostate cancer, potentially improving their quality of life.

How similar studies have performed: Other studies have shown promise with robotic-assisted treatments for prostate conditions, suggesting potential for success with this novel approach.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* International Prostate Symptom Score (IPSS) ≥ 8
* Gleason Grade Group 1-3
* Prostate-specific Antigen (PSA) ≤20ng/mL
* Cancer stage less than or equal to T2c

Exclusion Criteria:

* Patients with previous surgical treatment of benign prostatic hyperplasia
* MRI evidence of extracapsular extension of cancer
* Any severe illness that would prevent complete study participation or confound study results

Where this trial is running

La Mesa, California and 5 other locations

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.

View on ClinicalTrials.gov →

Conditions: Benign Prostatic Hyperplasia, Localized Prostate Cancer, AQUABEAM, AQUABEAM Robotic System, Aquablation, Aquablation therapy, Robotic Waterjet Treatment, RWT

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.