Clinical trial Recruiting at 1 site Interventional Ages 18 and up

Aromatherapy to reduce nausea and vomiting after total joint replacement

Official title: A Randomized Control Trial on the Efficacy of Aromatherapy in Reducing Postoperative Nausea and Vomiting in Total Joint Replacement Patients

Run by Hong Kong Buddhist Hospital · NCT07281885 · Data updated 2026-11-12

This trial will test whether scented patches (lavender-sandalwood or orange-ginger) reduce postoperative nausea and vomiting in adults having total joint replacement surgery.

Quick facts

Study typeInterventional
Ages18 Years and up
SexAll
Enrollment159 (estimated)
SponsorHong Kong Buddhist Hospital
Academic / other
Locations1 site (Wong Tai Sin, Hong Kong)
StatusRecruiting
StartedSeptember 1, 2025
Main results expectedDecember 2026
Study endsDecember 2026
Registry record updatedJanuary 7, 2026
Trial IDNCT07281885 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Adults aged 18 or older scheduled for total joint replacement at Hong Kong Buddhist Hospital who can provide consent and are not allergic to the patch ingredients or micropore tape.

Probably not a fit

Patients with cognitive impairment, allergies to lavender, orange, ginger, sandalwood, or micropore tape, or those already receiving other PONV therapies are not eligible and would not receive potential benefit from this intervention.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This randomized controlled trial will enroll 159 adults undergoing total joint replacement and randomize them into three groups: aromatherapy patches plus standard care, placebo patch plus standard care, or standard care alone. Nausea and vomiting will be measured with the Rhodes Index of Nausea, Vomiting, and Retching at baseline, 30 minutes after the intervention, and every 12 hours after surgery. Patient satisfaction will be captured using a 5-point Likert scale, with primary analysis focused on RINVR scores and secondary analysis on satisfaction. The trial is conducted at Hong Kong Buddhist Hospital with collaborators from Queen Elizabeth Hospital.

Why it matters

Potential benefit: If successful, patients may experience less postoperative nausea and vomiting and higher satisfaction during recovery, potentially reducing discomfort and improving early recovery.

How similar studies have gone: Previous small randomized trials and systematic reviews of aromatherapy for postoperative and chemotherapy-related nausea have reported mixed but sometimes positive results, so the approach has preliminary support though not definitive proof.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Adults aged 18 or above
* Patients scheduled for total joint replacement surgery at the HKBH

Exclusion Criteria:

* Cognitive impairments
* Allergy to lavender, orange, ginger, or sandalwood
* Allergy to micro-pore tape
* Allergy to opioid medication
* Undergoing other therapeutic treatment for PONV control, except prescribed medications

Where it's running

  • Hong Kong Buddhist Hospital
    Wong Tai Sin, Hong Kong, Hong Kong
    Recruiting

Study contacts

  • Principal investigator: Choi Wan CHAN, APN (NURSING) — Hong Kong Buddhist Hospital
  • Study coordinator: Choi Wan CHAN, APN (NURSING)
  • Email: cw.chan1@ha.org.hk
  • Phone: 852-2339

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How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.